IPI:IPI00221382.3
Protein Information
| Protein | IPI:IPI00221382.3 |
|---|---|
| Gene Symbol | HMGCR |
| Protein Description | Isoform 2 of 3-hydroxy-3-methylglutaryl-coenzyme A reductase |
| Sequence Length | 835 |
| Mwt | 91961.035 Da |
| Sequence | MLSRLFRMHG LFVASHPWEV IVGTVTLTIC MMSMNMFTGN NKICGWNYEC PKFEEDVLSS DIIILTITRC IAILYIYFQF QNLRQLGSKY ILGIAGLFTI FSSFVFSTVV IHFLDKELTG LNEALPFFLL LIDLSRASTL AKFALSSNSQ DEVRENIARG MAILGPTFTL DALVECLVIG VGTMSGVRQL EIMCCFGCMS VLANYFVFMT FFPACVSLVL ELSRESREGR PIWQLSHFAR VLEEEENKPN PVTQRVKMIM SLGLVLVHAH SRWIADPSPQ NSTADTSKVS LGLDENVSKR IEPSVSLWQF YLSKMISMDI EQVITLSLAL LLAVKYIFFE QTETESTLSL KNPITSPVVT QKKVPDNCCR REPMLVRNNQ KCDSVEEETG INRERKVEVI KPLVAETDTP NRATFVVGNS SLLDTSSVLV TQEPEIELPR EPRPNEECLQ ILGNAEKGAK FLSDAEIIQL VNAKHIPAYK LETLMETHER GVSIRRQLLS KKLSEPSSLQ YLPYRDYNYS LLGGGASSRV LADGMTRGPV VRLPRACDSA EVKAWLETSE GFAVIKEAFD STSRFARLQK LHTSIAGRNL YIRFQSRSGD AMGMNMISKG TEKALSKLHE YFPEMQILAV SGNYCTDKKP AAINWIEGRG KSVVCEAVIP AKVVREVLKT TTEAMIEVNI NKNLVGSAMA GSIGGYNAHA ANIVTAIYIA CGQDAAQNVG SSNCITLMEA SGPTNEDLYI SCTMPSIEIG TVGGGTNLLP QQACLQMLGV QGACKDNPGE NARQLARIVC GTVMAGELSL MAALAAGHLV KSHMIHNRSK INLQDLQGAC TKKTA |
Modification Site Information
| Site Position | 142 |
|---|---|
| MS/MS spectra | 136 [show] |
| Best localized sequence | R.ASTLAK#FALSSNSQDEVR@.E |
| Matching Proteins |
|
| Site Position | 248 |
|---|---|
| MS/MS spectra | 229 [show] |
| Best localized sequence | R.VLEEEENK#PNPVTQR@.V |
| Matching Proteins |
|
| Site Position | 288 |
|---|---|
| MS/MS spectra | 206 [show] |
| Best localized sequence | R.WIADPSPQNSTADTSK#VSLGLDENVSK#R@.I |
| Matching Proteins |
|
| Site Position | 299 |
|---|---|
| MS/MS spectra | 243 [show] |
| Best localized sequence | K.VSLGLDENVSK#R@.I |
| Matching Proteins |
|
| Site Position | 351 |
|---|---|
| MS/MS spectra | 2 [show] |
| Best localized sequence | K.YIFFEQTETESTLSLK#NPITSPVVTQK.K |
| Matching Proteins |
|
| Site Position | 362 |
|---|---|
| MS/MS spectra | 223 [show] |
| Best localized sequence | K.NPITSPVVTQK#K.V |
| Matching Proteins |
|
| Site Position | 381 |
|---|---|
| MS/MS spectra | 34 [show] |
| Best localized sequence | R.NNQK#CDSVEEETGINR@.E |
| Matching Proteins |
|
| Site Position | 396 |
|---|---|
| MS/MS spectra | 2 [show] |
| Best localized sequence | R.K#VEVIKPLVAETDTPNR.A |
| Matching Proteins |
|
| Site Position | 401 |
|---|---|
| MS/MS spectra | 10 [show] |
| Best localized sequence | R.KVEVIK#PLVAETDTPNR.A |
| Matching Proteins |
|
| Site Position | 460 |
|---|---|
| MS/MS spectra | 17 [show] |
| Best localized sequence | K.GAK#FLSDAEIIQLVNAK.H |
| Matching Proteins |
|
| Site Position | 474 |
|---|---|
| MS/MS spectra | 60 [show] |
| Best localized sequence | K.FLSDAEIIQLVNAK#HIPAYK.L |
| Matching Proteins |
|
| Site Position | 480 |
|---|---|
| MS/MS spectra | 31 [show] |
| Best localized sequence | K.HIPAYK#LETLMETHER@.G |
| Matching Proteins |
|
| Site Position | 502 |
|---|---|
| MS/MS spectra | 31 [show] |
| Best localized sequence | K.K#LSEPSSLQYLPYR@.D |
| Matching Proteins |
|
| Site Position | 566 |
|---|---|
| MS/MS spectra | 12 [show] |
| Best localized sequence | K.AWLETSEGFAVIK#EAFDSTSR@.F |
| Matching Proteins |
|
| Site Position | 580 |
|---|---|
| MS/MS spectra | 6 [show] |
| Best localized sequence | R.LQK#LHTSIAGR@.N |
| Matching Proteins |
|
| Site Position | 609 |
|---|---|
| MS/MS spectra | 39 [show] |
| Best localized sequence | R.SGDAMGMNMISK#GTEK.A |
| Matching Proteins |
|
| Site Position | 613 |
|---|---|
| MS/MS spectra | 1 [show] |
| Best localized sequence | K.GTEK#ALSK.L |
| Matching Proteins |
|
| Site Position | 639 |
|---|---|
| MS/MS spectra | 33 [show] |
| Best localized sequence | K.K#PAAINWIEGR@.G |
| Matching Proteins |
|
| Site Position | 651 |
|---|---|
| MS/MS spectra | 4 [show] |
| Best localized sequence | R.GK#SVVCEAVIPAK.V |
| Matching Proteins |
|