IPI:IPI00021770.1
Protein Information
| Protein | IPI:IPI00021770.1 |
|---|---|
| Gene Symbol | HMGCR |
| Protein Description | Isoform 1 of 3-hydroxy-3-methylglutaryl-coenzyme A reductase |
| Sequence Length | 888 |
| Mwt | 97412.61 Da |
| Sequence | MLSRLFRMHG LFVASHPWEV IVGTVTLTIC MMSMNMFTGN NKICGWNYEC PKFEEDVLSS DIIILTITRC IAILYIYFQF QNLRQLGSKY ILGIAGLFTI FSSFVFSTVV IHFLDKELTG LNEALPFFLL LIDLSRASTL AKFALSSNSQ DEVRENIARG MAILGPTFTL DALVECLVIG VGTMSGVRQL EIMCCFGCMS VLANYFVFMT FFPACVSLVL ELSRESREGR PIWQLSHFAR VLEEEENKPN PVTQRVKMIM SLGLVLVHAH SRWIADPSPQ NSTADTSKVS LGLDENVSKR IEPSVSLWQF YLSKMISMDI EQVITLSLAL LLAVKYIFFE QTETESTLSL KNPITSPVVT QKKVPDNCCR REPMLVRNNQ KCDSVEEETG INRERKVEVI KPLVAETDTP NRATFVVGNS SLLDTSSVLV TQEPEIELPR EPRPNEECLQ ILGNAEKGAK FLSDAEIIQL VNAKHIPAYK LETLMETHER GVSIRRQLLS KKLSEPSSLQ YLPYRDYNYS LVMGACCENV IGYMPIPVGV AGPLCLDEKE FQVPMATTEG CLVASTNRGC RAIGLGGGAS SRVLADGMTR GPVVRLPRAC DSAEVKAWLE TSEGFAVIKE AFDSTSRFAR LQKLHTSIAG RNLYIRFQSR SGDAMGMNMI SKGTEKALSK LHEYFPEMQI LAVSGNYCTD KKPAAINWIE GRGKSVVCEA VIPAKVVREV LKTTTEAMIE VNINKNLVGS AMAGSIGGYN AHAANIVTAI YIACGQDAAQ NVGSSNCITL MEASGPTNED LYISCTMPSI EIGTVGGGTN LLPQQACLQM LGVQGACKDN PGENARQLAR IVCGTVMAGE LSLMAALAAG HLVKSHMIHN RSKINLQDLQ GACTKKTA |
Modification Site Information
| Site Position | 142 |
|---|---|
| MS/MS spectra | 136 [show] |
| Best localized sequence | R.ASTLAK#FALSSNSQDEVR@.E |
| Matching Proteins |
|
| Site Position | 248 |
|---|---|
| MS/MS spectra | 229 [show] |
| Best localized sequence | R.VLEEEENK#PNPVTQR@.V |
| Matching Proteins |
|
| Site Position | 288 |
|---|---|
| MS/MS spectra | 206 [show] |
| Best localized sequence | R.WIADPSPQNSTADTSK#VSLGLDENVSK#R@.I |
| Matching Proteins |
|
| Site Position | 299 |
|---|---|
| MS/MS spectra | 243 [show] |
| Best localized sequence | K.VSLGLDENVSK#R@.I |
| Matching Proteins |
|
| Site Position | 351 |
|---|---|
| MS/MS spectra | 2 [show] |
| Best localized sequence | K.YIFFEQTETESTLSLK#NPITSPVVTQK.K |
| Matching Proteins |
|
| Site Position | 362 |
|---|---|
| MS/MS spectra | 223 [show] |
| Best localized sequence | K.NPITSPVVTQK#K.V |
| Matching Proteins |
|
| Site Position | 381 |
|---|---|
| MS/MS spectra | 34 [show] |
| Best localized sequence | R.NNQK#CDSVEEETGINR@.E |
| Matching Proteins |
|
| Site Position | 396 |
|---|---|
| MS/MS spectra | 2 [show] |
| Best localized sequence | R.K#VEVIKPLVAETDTPNR.A |
| Matching Proteins |
|
| Site Position | 401 |
|---|---|
| MS/MS spectra | 10 [show] |
| Best localized sequence | R.KVEVIK#PLVAETDTPNR.A |
| Matching Proteins |
|
| Site Position | 460 |
|---|---|
| MS/MS spectra | 17 [show] |
| Best localized sequence | K.GAK#FLSDAEIIQLVNAK.H |
| Matching Proteins |
|
| Site Position | 474 |
|---|---|
| MS/MS spectra | 60 [show] |
| Best localized sequence | K.FLSDAEIIQLVNAK#HIPAYK.L |
| Matching Proteins |
|
| Site Position | 480 |
|---|---|
| MS/MS spectra | 31 [show] |
| Best localized sequence | K.HIPAYK#LETLMETHER@.G |
| Matching Proteins |
|
| Site Position | 502 |
|---|---|
| MS/MS spectra | 31 [show] |
| Best localized sequence | K.K#LSEPSSLQYLPYR@.D |
| Matching Proteins |
|
| Site Position | 619 |
|---|---|
| MS/MS spectra | 12 [show] |
| Best localized sequence | K.AWLETSEGFAVIK#EAFDSTSR@.F |
| Matching Proteins |
|
| Site Position | 633 |
|---|---|
| MS/MS spectra | 6 [show] |
| Best localized sequence | R.LQK#LHTSIAGR@.N |
| Matching Proteins |
|
| Site Position | 662 |
|---|---|
| MS/MS spectra | 39 [show] |
| Best localized sequence | R.SGDAMGMNMISK#GTEK.A |
| Matching Proteins |
|
| Site Position | 666 |
|---|---|
| MS/MS spectra | 1 [show] |
| Best localized sequence | K.GTEK#ALSK.L |
| Matching Proteins |
|
| Site Position | 692 |
|---|---|
| MS/MS spectra | 33 [show] |
| Best localized sequence | K.K#PAAINWIEGR@.G |
| Matching Proteins |
|
| Site Position | 704 |
|---|---|
| MS/MS spectra | 4 [show] |
| Best localized sequence | R.GK#SVVCEAVIPAK.V |
| Matching Proteins |
|