IPI:IPI00186711.4
Protein Information
| Protein | IPI:IPI00186711.4 |
|---|---|
| Gene Symbol | PLEC1 |
| Protein Description | Isoform 2 of Plectin-1 |
| Sequence Length | 4574 |
| Mwt | 518156.628 Da |
| Sequence | MSGEDAEVRA VSEDVSNGSS GSPSPGDTLP WNLGKTQRSR RSGGGAGSNG SVLDPAERAV IRIADERDRV QKKTFTKWVN KHLIKAQRHI SDLYEDLRDG HNLISLLEVL SGDSLPREKG RMRFHKLQNV QIALDYLRHR QVKLVNIRND DIADGNPKLT LGLIWTIILH FQISDIQVSG QSEDMTAKEK LLLWSQRMVE GYQGLRCDNF TSSWRDGRLF NAIIHRHKPL LIDMNKVYRQ TNLENLDQAF SVAERDLGVT RLLDPEDVDV PQPDEKSIIT YVSSLYDAMP RVPDVQDGVR ANELQLRWQE YRELVLLLLQ WMRHHTAAFE ERRFPSSFEE IEILWSQFLK FKEMELPAKE ADKNRSKGIY QSLEGAVQAG QLKVPPGYHP LDVEKEWGKL HVAILEREKQ LRSEFERLEC LQRIVTKLQM EAGLCEEQLN QADALLQSDV RLLAAGKVPQ RAGEVERDLD KADSMIRLLF NDVQTLKDGR HPQGEQMYRR VYRLHERLVA IRTEYNLRLK AGVAAPATQV AQVTLQSVQR RPELEDSTLR YLQDLLAWVE ENQHRVDGAE WGVDLPSVEA QLGSHRGLHQ SIEEFRAKIE RARSDEGQLS PATRGAYRDC LGRLDLQYAK LLNSSKARLR SLESLHSFVA AATKELMWLN EKEEEEVGFD WSDRNTNMTA KKESYSALMR ELELKEKKIK ELQNAGDRLL REDHPARPTV ESFQAALQTQ WSWMLQLCCC IEAHLKENAA YFQFFSDVRE AEGQLQKLQE ALRRKYSCDR SATVTRLEDL LQDAQDEKEQ LNEYKGHLSG LAKRAKAVVQ LKPRHPAHPM RGRLPLLAVC DYKQVEVTVH KGDECQLVGP AQPSHWKVLS SSGSEAAVPS VCFLVPPPNQ EAQEAVTRLE AQHQALVTLW HQLHVDMKSL LAWQSLRRDV QLIRSWSLAT FRTLKPEEQR QALHSLELHY QAFLRDSQDA GGFGPEDRLM AEREYGSCSH HYQQLLQSLE QGAQEESRCQ RCISELKDIR LQLEACETRT VHRLRLPLDK EPARECAQRI AEQQKAQAEV EGLGKGVARL SAEAEKVLAL PEPSPAAPTL RSELELTLGK LEQVRSLSAI YLEKLKTISL VIRGTQGAEE VLRAHEEQLK EAQAVPATLP ELEATKASLK KLRAQAEAQQ PTFDALRDEL RGAQEVGERL QQRHGERDVE VERWRERVAQ LLERWQAVLA QTDVRQRELE QLGRQLRYYR ESADPLGAWL QDARRRQEQI QAMPLADSQA VREQLRQEQA LLEEIERHGE KVEECQRFAK QYINAIKDYE LQLVTYKAQL EPVASPAKKP KVQSGSESVI QEYVDLRTHY SELTTLTSQY IKFISETLRR MEEEERLAEQ QRAEERERLA EVEAALEKQR QLAEAHAQAK AQAEREAKEL QQRMQEEVVR REEAAVDAQQ QKRSIQEELQ QLRQSSEAEI QAKARQAEAA ERSRLRIEEE IRVVRLQLEA TERQRGGAEG ELQALRARAE EAEAQKRQAQ EEAERLRRQV QDESQRKRQA EVELASRVKA EAEAAREKQR ALQALEELRL QAEEAERRLR QAEVERARQV QVALETAQRS AEAELQSKRA SFAEKTAQLE RSLQEEHVAV AQLREEAERR AQQQAEAERA REEAERELER WQLKANEALR LRLQAEEVAQ QKSLAQAEAE KQKEEAEREA RRRGKAEEQA VRQRELAEQE LEKQRQLAEG TAQQRLAAEQ ELIRLRAETE QGEQQRQLLE EELARLQREA AAATQKRQEL EAELAKVRAE MEVLLASKAR AEEESRSTSE KSKQRLEAEA GRFRELAEEA ARLRALAEEA KRQRQLAEED AARQRAEAER VLAEKLAAIG EATRLKTEAE IALKEKEAEN ERLRRLAEDE AFQRRRLEEQ AAQHKADIEE RLAQLRKASD SELERQKGLV EDTLRQRRQV EEEILALKAS FEKAAAGKAE LELELGRIRS NAEDTLRSKE QAELEAARQR QLAAEEERRR REAEERVQKS LAAEEEAARQ RKAALEEVER LKAKVEEARR LRERAEQESA RQLQLAQEAA QKRLQAEEKA HAFAVQQKEQ ELQQTLQQEQ SVLDQLRGEA EAARRAAEEA EEARVQAERE AAQSRRQVEE AERLKQSAEE QAQARAQAQA AAEKLRKEAE QEAARRAQAE QAALRQKQAA DAEMEKHKKF AEQTLRQKAQ VEQELTTLRL QLEETDHQKN LLDEELQRLK AEATEAARQR SQVEEELFSV RVQMEELSKL KARIEAENRA LILRDKDNTQ RFLQEEAEKM KQVAEEAARL SVAAQEAARL RQLAEEDLAQ QRALAEKMLK EKMQAVQEAT RLKAEAELLQ QQKELAQEQA RRLQEDKEQM AQQLAEETQG FQRTLEAERQ RQLEMSAEAE RLKLRVAEMS RAQARAEEDA QRFRKQAEEI GEKLHRTELA TQEKVTLVQT LEIQRQQSDH DAERLREAIA ELEREKEKLQ QEAKLLQLKS EEMQTVQQEQ LLQETQALQQ SFLSEKDSLL QRERFIEQEK AKLEQLFQDE VAKAQQLREE QQRQQQQMEQ ERQRLVASME EARRRQHEAE EGVRRKQEEL QQLEQQRRQQ EELLAEENQR LREQLQLLEE QHRAALAHSE EVTASQVAAT KTLPNGRDAL DGPAAEAEPE HSFDGLRRKV SAQRLQEAGI LSAEELQRLA QGHTTVDELA RREDVRHYLQ GRSSIAGLLL KATNEKLSVY AALQRQLLSP GTALILLEAQ AASGFLLDPV RNRRLTVNEA VKEGVVGPEL HHKLLSAERA VTGYKDPYTG QQISLFQAMQ KGLIVREHGI RLLEAQIATG GVIDPVHSHR VPVDVAYRRG YFDEEMNRVL ADPSDDTKGF FDPNTHENLT YLQLLERCVE DPETGLCLLP LTDKAAKGGE LVYTDSEARD VFEKATVSAP FGKFQGKTVT IWEIINSEYF TAEQRRDLLR QFRTGRITVE KIIKIIITVV EEQEQKGRLC FEGLRSLVPA AELLESRVID RELYQQLQRG ERSVRDVAEV DTVRRALRGA NVIAGVWLEE AGQKLSIYNA LKKDLLPSDM AVALLEAQAG TGHIIDPATS ARLTVDEAVR AGLVGPEFHE KLLSAEKAVT GYRDPYTGQS VSLFQALKKG LIPREQGLRL LDAQLSTGGI VDPSKSHRVP LDVACARGCL DEETSRALSA PRADAKAYSD PSTGEPATYG ELQQRCRPDQ LTGLSLLPLS EKAARARQEE LYSELQARET FEKTPVEVPV GGFKGRTVTV WELISSEYFT AEQRQELLRQ FRTGKVTVEK VIKILITIVE EVETLRQERL SFSGLRAPVP ASELLASGVL SRAQFEQLKD GKTTVKDLSE LGSVRTLLQG SGCLAGIYLE DTKEKVSIYE AMRRGLLRAT TAALLLEAQA ATGFLVDPVR NQRLYVHEAV KAGVVGPELH EQLLSAEKAV TGYRDPYSGS TISLFQAMQK GLVLRQHGIR LLEAQIATGG IIDPVHSHRV PVDVAYQRGY FSEEMNRVLA DPSDDTKGFF DPNTHENLTY RQLLERCVED PETGLRLLPL KGAEKAEVVE TTQVYTEEET RRAFEETQID IPGGGSHGGS TMSLWEVMQS DLIPEEQRAQ LMADFQAGRV TKERMIIIII EIIEKTEIIR QQGLASYDYV RRRLTAEDLF EARIISLETY NLLREGTRSL REALEAESAW CYLYGTGSVA GVYLPGSRQT LSIYQALKKG LLSAEVARLL LEAQAATGFL LDPVKGERLT VDEAVRKGLV GPELHDRLLS AERAVTGYRD PYTEQTISLF QAMKKELIPT EEALRLLDAQ LATGGIVDPR LGFHLPLEVA YQRGYLNKDT HDQLSEPSEV RSYVDPSTDE RLSYTQLLRR CRRDDGTGQL LLPLSDARKL TFRGLRKQIT MEELVRSQVM DEATALQLRE GLTSIEEVTK NLQKFLEGTS CIAGVFVDAT KERLSVYQAM KKGIIRPGTA FELLEAQAAT GYVIDPIKGL KLTVEEAVRM GIVGPEFKDK LLSAERAVTG YKDPYSGKLI SLFQAMKKGL ILKDHGIRLL EAQIATGGII DPEESHRLPV EVAYKRGLFD EEMNEILTDP SDDTKGFFDP NTEENLTYLQ LMERCITDPQ TGLCLLPLKE KKRERKTSSK SSVRKRRVVI VDPETGKEMS VYEAYRKGLI DHQTYLELSE QECEWEEITI SSSDGVVKSM IIDRRSGRQY DIDDAIAKNL IDRSALDQYR AGTLSITEFA DMLSGNAGGF RSRSSSVGSS SSYPISPAVS RTQLASWSDP TEETGPVAGI LDTETLEKVS ITEAMHRNLV DNITGQRLLE AQACTGGIID PSTGERFPVT DAVNKGLVDK IMVDRINLAQ KAFCGFEDPR TKTKMSAAQA LKKGWLYYEA GQRFLEVQYL TGGLIEPDTP GRVPLDEALQ RGTVDARTAQ KLRDVGAYSK YLTCPKTKLK ISYKDALDRS MVEEGTGLRL LEAAAQSTKG YYSPYSVSGS GSTAGSRTGS RTGSRAGSRR GSFDATGSGF SMTFSSSSYS SSGYGRRYAS GSSASLGGPE SAVA |
Modification Site Information
| Site Position | 359 |
|---|---|
| MS/MS spectra | 14 [show] |
| Best localized sequence | K.EMELPAK#EADK.N |
| Matching Proteins |
|
| Site Position | 367 |
|---|---|
| MS/MS spectra | 2 [show] |
| Best localized sequence | R.SK#GIYQSLEGAVQAGQLK.V |
| Matching Proteins |
|
| Site Position | 383 |
|---|---|
| MS/MS spectra | 8 [show] |
| Best localized sequence | K.GIYQSLEGAVQAGQLK#VPPGYHPLDVEK.E |
| Matching Proteins |
|
| Site Position | 471 |
|---|---|
| MS/MS spectra | 1 [show] |
| Best localized sequence | R.DLDK#ADSMIR.L |
| Matching Proteins |
|
| Site Position | 487 |
|---|---|
| MS/MS spectra | 9 [show] |
| Best localized sequence | R.LLFNDVQTLK#DGR.H |
| Matching Proteins |
|
| Site Position | 520 |
|---|---|
| MS/MS spectra | 22 [show] |
| Best localized sequence | R.LK#AGVAAPATQVAQVTLQSVQR.R |
| Matching Proteins |
|
| Site Position | 630 |
|---|---|
| MS/MS spectra | 13 [show] |
| Best localized sequence | R.LDLQYAK#LLNSSK.A |
| Matching Proteins |
|
| Site Position | 798 |
|---|---|
| MS/MS spectra | 53 [show] |
| Best localized sequence | R.LEDLLQDAQDEK#EQLNEYK.G |
| Matching Proteins |
|
| Site Position | 1055 |
|---|---|
| MS/MS spectra | 24 [show] |
| Best localized sequence | R.IAEQQK#AQAEVEGLGK.G |
| Matching Proteins |
|
| Site Position | 1076 |
|---|---|
| MS/MS spectra | 13 [show] |
| Best localized sequence | R.LSAEAEK#VLALPEPSPAAPTLR.S |
| Matching Proteins |
|
| Site Position | 1100 |
|---|---|
| MS/MS spectra | 431 [show] |
| Best localized sequence | R.SELELTLGK#LEQVR@.S |
| Matching Proteins |
|
| Site Position | 1140 |
|---|---|
| MS/MS spectra | 137 [show] |
| Best localized sequence | R.AHEEQLK#EAQAVPATLPELEATK.A |
| Matching Proteins |
|
| Site Position | 1300 |
|---|---|
| MS/MS spectra | 29 [show] |
| Best localized sequence | R.FAK#QYINAIK.D |
| Matching Proteins |
|
| Site Position | 1307 |
|---|---|
| MS/MS spectra | 3 [show] |
| Best localized sequence | K.QYINAIK#DYELQLVTYK.A |
| Matching Proteins |
|
| Site Position | 1317 |
|---|---|
| MS/MS spectra | 45 [show] |
| Best localized sequence | K.DYELQLVTYK#AQLEPVASPAK.K |
| Matching Proteins |
|
| Site Position | 1398 |
|---|---|
| MS/MS spectra | 2 [show] |
| Best localized sequence | R.LAEVEAALEK#QR.Q |
| Matching Proteins |
|
| Site Position | 1608 |
|---|---|
| MS/MS spectra | 17 [show] |
| Best localized sequence | R.SAEAELQSK#R.A |
| Matching Proteins |
|
| Site Position | 2540 |
|---|---|
| MS/MS spectra | 1 [show] |
| Best localized sequence | R.FIEQEK#AK.L |
| Matching Proteins |
|
| Site Position | 2553 |
|---|---|
| MS/MS spectra | 1 [show] |
| Best localized sequence | K.LEQLFQDEVAK#AQQLR.E |
| Matching Proteins |
|
| Site Position | 2821 |
|---|---|
| MS/MS spectra | 8 [show] |
| Best localized sequence | K.DPYTGQQISLFQAMQK#GLIVR.E |
| Matching Proteins |
|
| Site Position | 2878 |
|---|---|
| MS/MS spectra | 13 [show] |
| Best localized sequence | R.VLADPSDDTK#GFFDPNTHENLTYLQLLER.C |
| Matching Proteins |
|
| Site Position | 2917 |
|---|---|
| MS/MS spectra | 3 [show] |
| Best localized sequence | K.AAK#GGELVYTDSEAR.D |
| Matching Proteins |
|
| Site Position | 3206 |
|---|---|
| MS/MS spectra | 52 [show] |
| Best localized sequence | R.ADAK#AYSDPSTGEPATYGELQQR.C |
| Matching Proteins |
|
| Site Position | 3274 |
|---|---|
| MS/MS spectra | 19 [show] |
| Best localized sequence | K.TPVEVPVGGFK#GR.T |
| Matching Proteins |
|
| Site Position | 3480 |
|---|---|
| MS/MS spectra | 3 [show] |
| Best localized sequence | R.DPYSGSTISLFQAMQK#GLVLR.Q |
| Matching Proteins |
|
| Site Position | 3537 |
|---|---|
| MS/MS spectra | 12 [show] |
| Best localized sequence | R.VLADPSDDTK#GFFDPNTHENLTYR@.Q |
| Matching Proteins |
|
| Site Position | 3858 |
|---|---|
| MS/MS spectra | 17 [show] |
| Best localized sequence | R.GYLNK#DTHDQLSEPSEVR.S |
| Matching Proteins |
|
| Site Position | 3917 |
|---|---|
| MS/MS spectra | 1 [show] |
| Best localized sequence | R.K#QITMEELVR.S |
| Matching Proteins |
|
| Site Position | 3950 |
|---|---|
| MS/MS spectra | 2 [show] |
| Best localized sequence | R.EGLTSIEEVTK#NLQK.F |
| Matching Proteins |
|
| Site Position | 4028 |
|---|---|
| MS/MS spectra | 1 [show] |
| Best localized sequence | R.MGIVGPEFK#DK.L |
| Matching Proteins |
|
| Site Position | 4042 |
|---|---|
| MS/MS spectra | 1 [show] |
| Best localized sequence | R.AVTGYK#DPYSGK.L |
| Matching Proteins |
|
| Site Position | 4048 |
|---|---|
| MS/MS spectra | 1 [show] |
| Best localized sequence | K.DPYSGK#LISLFQAMK.K |
| Matching Proteins |
|
| Site Position | 4095 |
|---|---|
| MS/MS spectra | 4 [show] |
| Best localized sequence | R.LPVEVAYK#R.G |
| Matching Proteins |
|
| Site Position | 4177 |
|---|---|
| MS/MS spectra | 24 [show] |
| Best localized sequence | R.VVIVDPETGK#EMSVYEAYR.K |
| Matching Proteins |
|
| Site Position | 4238 |
|---|---|
| MS/MS spectra | 20 [show] |
| Best localized sequence | R.QYDIDDAIAK#NLIDR.S |
| Matching Proteins |
|
| Site Position | 4403 |
|---|---|
| MS/MS spectra | 1 [show] |
| Best localized sequence | K.K#GWLYYEAGQR.F |
| Matching Proteins |
|
| Site Position | 4499 |
|---|---|
| MS/MS spectra | 140 [show] |
| Best localized sequence | R.LLEAAAQSTK#GYYSPYSVSGSGSTAGSR@.T |
| Matching Proteins |
|