IPI:IPI00398775.3
Protein Information
| Protein | IPI:IPI00398775.3 |
|---|---|
| Gene Symbol | PLEC1 |
| Protein Description | Isoform 9 of Plectin-1 |
| Sequence Length | 4533 |
| Mwt | 514460.788 Da |
| Sequence | MAGPLPDEQD FIQAYEEVRE KYKDERDRVQ KKTFTKWVNK HLIKAQRHIS DLYEDLRDGH NLISLLEVLS GDSLPREKGR MRFHKLQNVQ IALDYLRHRQ VKLVNIRNDD IADGNPKLTL GLIWTIILHF QISDIQVSGQ SEDMTAKEKL LLWSQRMVEG YQGLRCDNFT SSWRDGRLFN AIIHRHKPLL IDMNKVYRQT NLENLDQAFS VAERDLGVTR LLDPEDVDVP QPDEKSIITY VSSLYDAMPR VPDVQDGVRA NELQLRWQEY RELVLLLLQW MRHHTAAFEE RRFPSSFEEI EILWSQFLKF KEMELPAKEA DKNRSKGIYQ SLEGAVQAGQ LKVPPGYHPL DVEKEWGKLH VAILEREKQL RSEFERLECL QRIVTKLQME AGLCEEQLNQ ADALLQSDVR LLAAGKVPQR AGEVERDLDK ADSMIRLLFN DVQTLKDGRH PQGEQMYRRV YRLHERLVAI RTEYNLRLKA GVAAPATQVA QVTLQSVQRR PELEDSTLRY LQDLLAWVEE NQHRVDGAEW GVDLPSVEAQ LGSHRGLHQS IEEFRAKIER ARSDEGQLSP ATRGAYRDCL GRLDLQYAKL LNSSKARLRS LESLHSFVAA ATKELMWLNE KEEEEVGFDW SDRNTNMTAK KESYSALMRE LELKEKKIKE LQNAGDRLLR EDHPARPTVE SFQAALQTQW SWMLQLCCCI EAHLKENAAY FQFFSDVREA EGQLQKLQEA LRRKYSCDRS ATVTRLEDLL QDAQDEKEQL NEYKGHLSGL AKRAKAVVQL KPRHPAHPMR GRLPLLAVCD YKQVEVTVHK GDECQLVGPA QPSHWKVLSS SGSEAAVPSV CFLVPPPNQE AQEAVTRLEA QHQALVTLWH QLHVDMKSLL AWQSLRRDVQ LIRSWSLATF RTLKPEEQRQ ALHSLELHYQ AFLRDSQDAG GFGPEDRLMA EREYGSCSHH YQQLLQSLEQ GAQEESRCQR CISELKDIRL QLEACETRTV HRLRLPLDKE PARECAQRIA EQQKAQAEVE GLGKGVARLS AEAEKVLALP EPSPAAPTLR SELELTLGKL EQVRSLSAIY LEKLKTISLV IRGTQGAEEV LRAHEEQLKE AQAVPATLPE LEATKASLKK LRAQAEAQQP TFDALRDELR GAQEVGERLQ QRHGERDVEV ERWRERVAQL LERWQAVLAQ TDVRQRELEQ LGRQLRYYRE SADPLGAWLQ DARRRQEQIQ AMPLADSQAV REQLRQEQAL LEEIERHGEK VEECQRFAKQ YINAIKDYEL QLVTYKAQLE PVASPAKKPK VQSGSESVIQ EYVDLRTHYS ELTTLTSQYI KFISETLRRM EEEERLAEQQ RAEERERLAE VEAALEKQRQ LAEAHAQAKA QAEREAKELQ QRMQEEVVRR EEAAVDAQQQ KRSIQEELQQ LRQSSEAEIQ AKARQAEAAE RSRLRIEEEI RVVRLQLEAT ERQRGGAEGE LQALRARAEE AEAQKRQAQE EAERLRRQVQ DESQRKRQAE VELASRVKAE AEAAREKQRA LQALEELRLQ AEEAERRLRQ AEVERARQVQ VALETAQRSA EAELQSKRAS FAEKTAQLER SLQEEHVAVA QLREEAERRA QQQAEAERAR EEAERELERW QLKANEALRL RLQAEEVAQQ KSLAQAEAEK QKEEAEREAR RRGKAEEQAV RQRELAEQEL EKQRQLAEGT AQQRLAAEQE LIRLRAETEQ GEQQRQLLEE ELARLQREAA AATQKRQELE AELAKVRAEM EVLLASKARA EEESRSTSEK SKQRLEAEAG RFRELAEEAA RLRALAEEAK RQRQLAEEDA ARQRAEAERV LAEKLAAIGE ATRLKTEAEI ALKEKEAENE RLRRLAEDEA FQRRRLEEQA AQHKADIEER LAQLRKASDS ELERQKGLVE DTLRQRRQVE EEILALKASF EKAAAGKAEL ELELGRIRSN AEDTLRSKEQ AELEAARQRQ LAAEEERRRR EAEERVQKSL AAEEEAARQR KAALEEVERL KAKVEEARRL RERAEQESAR QLQLAQEAAQ KRLQAEEKAH AFAVQQKEQE LQQTLQQEQS VLDQLRGEAE AARRAAEEAE EARVQAEREA AQSRRQVEEA ERLKQSAEEQ AQARAQAQAA AEKLRKEAEQ EAARRAQAEQ AALRQKQAAD AEMEKHKKFA EQTLRQKAQV EQELTTLRLQ LEETDHQKNL LDEELQRLKA EATEAARQRS QVEEELFSVR VQMEELSKLK ARIEAENRAL ILRDKDNTQR FLQEEAEKMK QVAEEAARLS VAAQEAARLR QLAEEDLAQQ RALAEKMLKE KMQAVQEATR LKAEAELLQQ QKELAQEQAR RLQEDKEQMA QQLAEETQGF QRTLEAERQR QLEMSAEAER LKLRVAEMSR AQARAEEDAQ RFRKQAEEIG EKLHRTELAT QEKVTLVQTL EIQRQQSDHD AERLREAIAE LEREKEKLQQ EAKLLQLKSE EMQTVQQEQL LQETQALQQS FLSEKDSLLQ RERFIEQEKA KLEQLFQDEV AKAQQLREEQ QRQQQQMEQE RQRLVASMEE ARRRQHEAEE GVRRKQEELQ QLEQQRRQQE ELLAEENQRL REQLQLLEEQ HRAALAHSEE VTASQVAATK TLPNGRDALD GPAAEAEPEH SFDGLRRKVS AQRLQEAGIL SAEELQRLAQ GHTTVDELAR REDVRHYLQG RSSIAGLLLK ATNEKLSVYA ALQRQLLSPG TALILLEAQA ASGFLLDPVR NRRLTVNEAV KEGVVGPELH HKLLSAERAV TGYKDPYTGQ QISLFQAMQK GLIVREHGIR LLEAQIATGG VIDPVHSHRV PVDVAYRRGY FDEEMNRVLA DPSDDTKGFF DPNTHENLTY LQLLERCVED PETGLCLLPL TDKAAKGGEL VYTDSEARDV FEKATVSAPF GKFQGKTVTI WEIINSEYFT AEQRRDLLRQ FRTGRITVEK IIKIIITVVE EQEQKGRLCF EGLRSLVPAA ELLESRVIDR ELYQQLQRGE RSVRDVAEVD TVRRALRGAN VIAGVWLEEA GQKLSIYNAL KKDLLPSDMA VALLEAQAGT GHIIDPATSA RLTVDEAVRA GLVGPEFHEK LLSAEKAVTG YRDPYTGQSV SLFQALKKGL IPREQGLRLL DAQLSTGGIV DPSKSHRVPL DVACARGCLD EETSRALSAP RADAKAYSDP STGEPATYGE LQQRCRPDQL TGLSLLPLSE KAARARQEEL YSELQARETF EKTPVEVPVG GFKGRTVTVW ELISSEYFTA EQRQELLRQF RTGKVTVEKV IKILITIVEE VETLRQERLS FSGLRAPVPA SELLASGVLS RAQFEQLKDG KTTVKDLSEL GSVRTLLQGS GCLAGIYLED TKEKVSIYEA MRRGLLRATT AALLLEAQAA TGFLVDPVRN QRLYVHEAVK AGVVGPELHE QLLSAEKAVT GYRDPYSGST ISLFQAMQKG LVLRQHGIRL LEAQIATGGI IDPVHSHRVP VDVAYQRGYF SEEMNRVLAD PSDDTKGFFD PNTHENLTYR QLLERCVEDP ETGLRLLPLK GAEKAEVVET TQVYTEEETR RAFEETQIDI PGGGSHGGST MSLWEVMQSD LIPEEQRAQL MADFQAGRVT KERMIIIIIE IIEKTEIIRQ QGLASYDYVR RRLTAEDLFE ARIISLETYN LLREGTRSLR EALEAESAWC YLYGTGSVAG VYLPGSRQTL SIYQALKKGL LSAEVARLLL EAQAATGFLL DPVKGERLTV DEAVRKGLVG PELHDRLLSA ERAVTGYRDP YTEQTISLFQ AMKKELIPTE EALRLLDAQL ATGGIVDPRL GFHLPLEVAY QRGYLNKDTH DQLSEPSEVR SYVDPSTDER LSYTQLLRRC RRDDGTGQLL LPLSDARKLT FRGLRKQITM EELVRSQVMD EATALQLREG LTSIEEVTKN LQKFLEGTSC IAGVFVDATK ERLSVYQAMK KGIIRPGTAF ELLEAQAATG YVIDPIKGLK LTVEEAVRMG IVGPEFKDKL LSAERAVTGY KDPYSGKLIS LFQAMKKGLI LKDHGIRLLE AQIATGGIID PEESHRLPVE VAYKRGLFDE EMNEILTDPS DDTKGFFDPN TEENLTYLQL MERCITDPQT GLCLLPLKEK KRERKTSSKS SVRKRRVVIV DPETGKEMSV YEAYRKGLID HQTYLELSEQ ECEWEEITIS SSDGVVKSMI IDRRSGRQYD IDDAIAKNLI DRSALDQYRA GTLSITEFAD MLSGNAGGFR SRSSSVGSSS SYPISPAVSR TQLASWSDPT EETGPVAGIL DTETLEKVSI TEAMHRNLVD NITGQRLLEA QACTGGIIDP STGERFPVTD AVNKGLVDKI MVDRINLAQK AFCGFEDPRT KTKMSAAQAL KKGWLYYEAG QRFLEVQYLT GGLIEPDTPG RVPLDEALQR GTVDARTAQK LRDVGAYSKY LTCPKTKLKI SYKDALDRSM VEEGTGLRLL EAAAQSTKGY YSPYSVSGSG STAGSRTGSR TGSRAGSRRG SFDATGSGFS MTFSSSSYSS SGYGRRYASG SSASLGGPES AVA |
Modification Site Information
| Site Position | 318 |
|---|---|
| MS/MS spectra | 14 [show] |
| Best localized sequence | K.EMELPAK#EADK.N |
| Matching Proteins |
|
| Site Position | 326 |
|---|---|
| MS/MS spectra | 2 [show] |
| Best localized sequence | R.SK#GIYQSLEGAVQAGQLK.V |
| Matching Proteins |
|
| Site Position | 342 |
|---|---|
| MS/MS spectra | 8 [show] |
| Best localized sequence | K.GIYQSLEGAVQAGQLK#VPPGYHPLDVEK.E |
| Matching Proteins |
|
| Site Position | 430 |
|---|---|
| MS/MS spectra | 1 [show] |
| Best localized sequence | R.DLDK#ADSMIR.L |
| Matching Proteins |
|
| Site Position | 446 |
|---|---|
| MS/MS spectra | 9 [show] |
| Best localized sequence | R.LLFNDVQTLK#DGR.H |
| Matching Proteins |
|
| Site Position | 479 |
|---|---|
| MS/MS spectra | 22 [show] |
| Best localized sequence | R.LK#AGVAAPATQVAQVTLQSVQR.R |
| Matching Proteins |
|
| Site Position | 589 |
|---|---|
| MS/MS spectra | 13 [show] |
| Best localized sequence | R.LDLQYAK#LLNSSK.A |
| Matching Proteins |
|
| Site Position | 757 |
|---|---|
| MS/MS spectra | 53 [show] |
| Best localized sequence | R.LEDLLQDAQDEK#EQLNEYK.G |
| Matching Proteins |
|
| Site Position | 1014 |
|---|---|
| MS/MS spectra | 24 [show] |
| Best localized sequence | R.IAEQQK#AQAEVEGLGK.G |
| Matching Proteins |
|
| Site Position | 1035 |
|---|---|
| MS/MS spectra | 13 [show] |
| Best localized sequence | R.LSAEAEK#VLALPEPSPAAPTLR.S |
| Matching Proteins |
|
| Site Position | 1059 |
|---|---|
| MS/MS spectra | 431 [show] |
| Best localized sequence | R.SELELTLGK#LEQVR@.S |
| Matching Proteins |
|
| Site Position | 1099 |
|---|---|
| MS/MS spectra | 137 [show] |
| Best localized sequence | R.AHEEQLK#EAQAVPATLPELEATK.A |
| Matching Proteins |
|
| Site Position | 1259 |
|---|---|
| MS/MS spectra | 29 [show] |
| Best localized sequence | R.FAK#QYINAIK.D |
| Matching Proteins |
|
| Site Position | 1266 |
|---|---|
| MS/MS spectra | 3 [show] |
| Best localized sequence | K.QYINAIK#DYELQLVTYK.A |
| Matching Proteins |
|
| Site Position | 1276 |
|---|---|
| MS/MS spectra | 45 [show] |
| Best localized sequence | K.DYELQLVTYK#AQLEPVASPAK.K |
| Matching Proteins |
|
| Site Position | 1357 |
|---|---|
| MS/MS spectra | 2 [show] |
| Best localized sequence | R.LAEVEAALEK#QR.Q |
| Matching Proteins |
|
| Site Position | 1567 |
|---|---|
| MS/MS spectra | 17 [show] |
| Best localized sequence | R.SAEAELQSK#R.A |
| Matching Proteins |
|
| Site Position | 2499 |
|---|---|
| MS/MS spectra | 1 [show] |
| Best localized sequence | R.FIEQEK#AK.L |
| Matching Proteins |
|
| Site Position | 2512 |
|---|---|
| MS/MS spectra | 1 [show] |
| Best localized sequence | K.LEQLFQDEVAK#AQQLR.E |
| Matching Proteins |
|
| Site Position | 2780 |
|---|---|
| MS/MS spectra | 8 [show] |
| Best localized sequence | K.DPYTGQQISLFQAMQK#GLIVR.E |
| Matching Proteins |
|
| Site Position | 2837 |
|---|---|
| MS/MS spectra | 13 [show] |
| Best localized sequence | R.VLADPSDDTK#GFFDPNTHENLTYLQLLER.C |
| Matching Proteins |
|
| Site Position | 2876 |
|---|---|
| MS/MS spectra | 3 [show] |
| Best localized sequence | K.AAK#GGELVYTDSEAR.D |
| Matching Proteins |
|
| Site Position | 3165 |
|---|---|
| MS/MS spectra | 52 [show] |
| Best localized sequence | R.ADAK#AYSDPSTGEPATYGELQQR.C |
| Matching Proteins |
|
| Site Position | 3233 |
|---|---|
| MS/MS spectra | 19 [show] |
| Best localized sequence | K.TPVEVPVGGFK#GR.T |
| Matching Proteins |
|
| Site Position | 3439 |
|---|---|
| MS/MS spectra | 3 [show] |
| Best localized sequence | R.DPYSGSTISLFQAMQK#GLVLR.Q |
| Matching Proteins |
|
| Site Position | 3496 |
|---|---|
| MS/MS spectra | 12 [show] |
| Best localized sequence | R.VLADPSDDTK#GFFDPNTHENLTYR@.Q |
| Matching Proteins |
|
| Site Position | 3817 |
|---|---|
| MS/MS spectra | 17 [show] |
| Best localized sequence | R.GYLNK#DTHDQLSEPSEVR.S |
| Matching Proteins |
|
| Site Position | 3876 |
|---|---|
| MS/MS spectra | 1 [show] |
| Best localized sequence | R.K#QITMEELVR.S |
| Matching Proteins |
|
| Site Position | 3909 |
|---|---|
| MS/MS spectra | 2 [show] |
| Best localized sequence | R.EGLTSIEEVTK#NLQK.F |
| Matching Proteins |
|
| Site Position | 3987 |
|---|---|
| MS/MS spectra | 1 [show] |
| Best localized sequence | R.MGIVGPEFK#DK.L |
| Matching Proteins |
|
| Site Position | 4001 |
|---|---|
| MS/MS spectra | 1 [show] |
| Best localized sequence | R.AVTGYK#DPYSGK.L |
| Matching Proteins |
|
| Site Position | 4007 |
|---|---|
| MS/MS spectra | 1 [show] |
| Best localized sequence | K.DPYSGK#LISLFQAMK.K |
| Matching Proteins |
|
| Site Position | 4054 |
|---|---|
| MS/MS spectra | 4 [show] |
| Best localized sequence | R.LPVEVAYK#R.G |
| Matching Proteins |
|
| Site Position | 4136 |
|---|---|
| MS/MS spectra | 24 [show] |
| Best localized sequence | R.VVIVDPETGK#EMSVYEAYR.K |
| Matching Proteins |
|
| Site Position | 4197 |
|---|---|
| MS/MS spectra | 20 [show] |
| Best localized sequence | R.QYDIDDAIAK#NLIDR.S |
| Matching Proteins |
|
| Site Position | 4362 |
|---|---|
| MS/MS spectra | 1 [show] |
| Best localized sequence | K.K#GWLYYEAGQR.F |
| Matching Proteins |
|
| Site Position | 4458 |
|---|---|
| MS/MS spectra | 140 [show] |
| Best localized sequence | R.LLEAAAQSTK#GYYSPYSVSGSGSTAGSR@.T |
| Matching Proteins |
|