IPI:IPI00398002.6
Protein Information
| Protein | IPI:IPI00398002.6 |
|---|---|
| Gene Symbol | PLEC1 |
| Protein Description | Isoform 3 of Plectin-1 |
| Sequence Length | 4570 |
| Mwt | 517716.378 Da |
| Sequence | MSGEDAEVRA VSEDVSNGSS GSPSPGDTLP WNLGKTQRSR RSGGGAGSNG SVLDPAERAV IRIADERDRV QKKTFTKWVN KHLIKAQRHI SDLYEDLRDG HNLISLLEVL SGDSLPREKG RMRFHKLQNV QIALDYLRHR QVKLVNIRND DIADGNPKLT LGLIWTIILH FQISDIQVSG QSEDMTAKEK LLLWSQRMVE GYQGLRCDNF TSSWRDGRLF NAIIHRHKPL LIDMNKVYRQ TNLENLDQAF SVAERDLGVT RLLDPEDVDV PQPDEKSIIT YVSSLYDAMP RVPDVQDGEL QLRWQEYREL VLLLLQWMRH HTAAFEERRF PSSFEEIEIL WSQFLKFKEM ELPAKEADKN RSKGIYQSLE GAVQAGQLKV PPGYHPLDVE KEWGKLHVAI LEREKQLRSE FERLECLQRI VTKLQMEAGL CEEQLNQADA LLQSDVRLLA AGKVPQRAGE VERDLDKADS MIRLLFNDVQ TLKDGRHPQG EQMYRRVYRL HERLVAIRTE YNLRLKAGVA APATQVAQVT LQSVQRRPEL EDSTLRYLQD LLAWVEENQH RVDGAEWGVD LPSVEAQLGS HRGLHQSIEE FRAKIERARS DEGQLSPATR GAYRDCLGRL DLQYAKLLNS SKARLRSLES LHSFVAAATK ELMWLNEKEE EEVGFDWSDR NTNMTAKKES YSALMRELEL KEKKIKELQN AGDRLLREDH PARPTVESFQ AALQTQWSWM LQLCCCIEAH LKENAAYFQF FSDVREAEGQ LQKLQEALRR KYSCDRSATV TRLEDLLQDA QDEKEQLNEY KGHLSGLAKR AKAVVQLKPR HPAHPMRGRL PLLAVCDYKQ VEVTVHKGDE CQLVGPAQPS HWKVLSSSGS EAAVPSVCFL VPPPNQEAQE AVTRLEAQHQ ALVTLWHQLH VDMKSLLAWQ SLRRDVQLIR SWSLATFRTL KPEEQRQALH SLELHYQAFL RDSQDAGGFG PEDRLMAERE YGSCSHHYQQ LLQSLEQGAQ EESRCQRCIS ELKDIRLQLE ACETRTVHRL RLPLDKEPAR ECAQRIAEQQ KAQAEVEGLG KGVARLSAEA EKVLALPEPS PAAPTLRSEL ELTLGKLEQV RSLSAIYLEK LKTISLVIRG TQGAEEVLRA HEEQLKEAQA VPATLPELEA TKASLKKLRA QAEAQQPTFD ALRDELRGAQ EVGERLQQRH GERDVEVERW RERVAQLLER WQAVLAQTDV RQRELEQLGR QLRYYRESAD PLGAWLQDAR RRQEQIQAMP LADSQAVREQ LRQEQALLEE IERHGEKVEE CQRFAKQYIN AIKDYELQLV TYKAQLEPVA SPAKKPKVQS GSESVIQEYV DLRTHYSELT TLTSQYIKFI SETLRRMEEE ERLAEQQRAE ERERLAEVEA ALEKQRQLAE AHAQAKAQAE REAKELQQRM QEEVVRREEA AVDAQQQKRS IQEELQQLRQ SSEAEIQAKA RQAEAAERSR LRIEEEIRVV RLQLEATERQ RGGAEGELQA LRARAEEAEA QKRQAQEEAE RLRRQVQDES QRKRQAEVEL ASRVKAEAEA AREKQRALQA LEELRLQAEE AERRLRQAEV ERARQVQVAL ETAQRSAEAE LQSKRASFAE KTAQLERSLQ EEHVAVAQLR EEAERRAQQQ AEAERAREEA ERELERWQLK ANEALRLRLQ AEEVAQQKSL AQAEAEKQKE EAEREARRRG KAEEQAVRQR ELAEQELEKQ RQLAEGTAQQ RLAAEQELIR LRAETEQGEQ QRQLLEEELA RLQREAAAAT QKRQELEAEL AKVRAEMEVL LASKARAEEE SRSTSEKSKQ RLEAEAGRFR ELAEEAARLR ALAEEAKRQR QLAEEDAARQ RAEAERVLAE KLAAIGEATR LKTEAEIALK EKEAENERLR RLAEDEAFQR RRLEEQAAQH KADIEERLAQ LRKASDSELE RQKGLVEDTL RQRRQVEEEI LALKASFEKA AAGKAELELE LGRIRSNAED TLRSKEQAEL EAARQRQLAA EEERRRREAE ERVQKSLAAE EEAARQRKAA LEEVERLKAK VEEARRLRER AEQESARQLQ LAQEAAQKRL QAEEKAHAFA VQQKEQELQQ TLQQEQSVLD QLRGEAEAAR RAAEEAEEAR VQAEREAAQS RRQVEEAERL KQSAEEQAQA RAQAQAAAEK LRKEAEQEAA RRAQAEQAAL RQKQAADAEM EKHKKFAEQT LRQKAQVEQE LTTLRLQLEE TDHQKNLLDE ELQRLKAEAT EAARQRSQVE EELFSVRVQM EELSKLKARI EAENRALILR DKDNTQRFLQ EEAEKMKQVA EEAARLSVAA QEAARLRQLA EEDLAQQRAL AEKMLKEKMQ AVQEATRLKA EAELLQQQKE LAQEQARRLQ EDKEQMAQQL AEETQGFQRT LEAERQRQLE MSAEAERLKL RVAEMSRAQA RAEEDAQRFR KQAEEIGEKL HRTELATQEK VTLVQTLEIQ RQQSDHDAER LREAIAELER EKEKLQQEAK LLQLKSEEMQ TVQQEQLLQE TQALQQSFLS EKDSLLQRER FIEQEKAKLE QLFQDEVAKA QQLREEQQRQ QQQMEQERQR LVASMEEARR RQHEAEEGVR RKQEELQQLE QQRRQQEELL AEENQRLREQ LQLLEEQHRA ALAHSEEVTA SQVAATKTLP NGRDALDGPA AEAEPEHSFD GLRRKVSAQR LQEAGILSAE ELQRLAQGHT TVDELARRED VRHYLQGRSS IAGLLLKATN EKLSVYAALQ RQLLSPGTAL ILLEAQAASG FLLDPVRNRR LTVNEAVKEG VVGPELHHKL LSAERAVTGY KDPYTGQQIS LFQAMQKGLI VREHGIRLLE AQIATGGVID PVHSHRVPVD VAYRRGYFDE EMNRVLADPS DDTKGFFDPN THENLTYLQL LERCVEDPET GLCLLPLTDK AAKGGELVYT DSEARDVFEK ATVSAPFGKF QGKTVTIWEI INSEYFTAEQ RRDLLRQFRT GRITVEKIIK IIITVVEEQE QKGRLCFEGL RSLVPAAELL ESRVIDRELY QQLQRGERSV RDVAEVDTVR RALRGANVIA GVWLEEAGQK LSIYNALKKD LLPSDMAVAL LEAQAGTGHI IDPATSARLT VDEAVRAGLV GPEFHEKLLS AEKAVTGYRD PYTGQSVSLF QALKKGLIPR EQGLRLLDAQ LSTGGIVDPS KSHRVPLDVA CARGCLDEET SRALSAPRAD AKAYSDPSTG EPATYGELQQ RCRPDQLTGL SLLPLSEKAA RARQEELYSE LQARETFEKT PVEVPVGGFK GRTVTVWELI SSEYFTAEQR QELLRQFRTG KVTVEKVIKI LITIVEEVET LRQERLSFSG LRAPVPASEL LASGVLSRAQ FEQLKDGKTT VKDLSELGSV RTLLQGSGCL AGIYLEDTKE KVSIYEAMRR GLLRATTAAL LLEAQAATGF LVDPVRNQRL YVHEAVKAGV VGPELHEQLL SAEKAVTGYR DPYSGSTISL FQAMQKGLVL RQHGIRLLEA QIATGGIIDP VHSHRVPVDV AYQRGYFSEE MNRVLADPSD DTKGFFDPNT HENLTYRQLL ERCVEDPETG LRLLPLKGAE KAEVVETTQV YTEEETRRAF EETQIDIPGG GSHGGSTMSL WEVMQSDLIP EEQRAQLMAD FQAGRVTKER MIIIIIEIIE KTEIIRQQGL ASYDYVRRRL TAEDLFEARI ISLETYNLLR EGTRSLREAL EAESAWCYLY GTGSVAGVYL PGSRQTLSIY QALKKGLLSA EVARLLLEAQ AATGFLLDPV KGERLTVDEA VRKGLVGPEL HDRLLSAERA VTGYRDPYTE QTISLFQAMK KELIPTEEAL RLLDAQLATG GIVDPRLGFH LPLEVAYQRG YLNKDTHDQL SEPSEVRSYV DPSTDERLSY TQLLRRCRRD DGTGQLLLPL SDARKLTFRG LRKQITMEEL VRSQVMDEAT ALQLREGLTS IEEVTKNLQK FLEGTSCIAG VFVDATKERL SVYQAMKKGI IRPGTAFELL EAQAATGYVI DPIKGLKLTV EEAVRMGIVG PEFKDKLLSA ERAVTGYKDP YSGKLISLFQ AMKKGLILKD HGIRLLEAQI ATGGIIDPEE SHRLPVEVAY KRGLFDEEMN EILTDPSDDT KGFFDPNTEE NLTYLQLMER CITDPQTGLC LLPLKEKKRE RKTSSKSSVR KRRVVIVDPE TGKEMSVYEA YRKGLIDHQT YLELSEQECE WEEITISSSD GVVKSMIIDR RSGRQYDIDD AIAKNLIDRS ALDQYRAGTL SITEFADMLS GNAGGFRSRS SSVGSSSSYP ISPAVSRTQL ASWSDPTEET GPVAGILDTE TLEKVSITEA MHRNLVDNIT GQRLLEAQAC TGGIIDPSTG ERFPVTDAVN KGLVDKIMVD RINLAQKAFC GFEDPRTKTK MSAAQALKKG WLYYEAGQRF LEVQYLTGGL IEPDTPGRVP LDEALQRGTV DARTAQKLRD VGAYSKYLTC PKTKLKISYK DALDRSMVEE GTGLRLLEAA AQSTKGYYSP YSVSGSGSTA GSRTGSRTGS RAGSRRGSFD ATGSGFSMTF SSSSYSSSGY GRRYASGSSA SLGGPESAVA |
Modification Site Information
| Site Position | 355 |
|---|---|
| MS/MS spectra | 14 [show] |
| Best localized sequence | K.EMELPAK#EADK.N |
| Matching Proteins |
|
| Site Position | 363 |
|---|---|
| MS/MS spectra | 2 [show] |
| Best localized sequence | R.SK#GIYQSLEGAVQAGQLK.V |
| Matching Proteins |
|
| Site Position | 379 |
|---|---|
| MS/MS spectra | 8 [show] |
| Best localized sequence | K.GIYQSLEGAVQAGQLK#VPPGYHPLDVEK.E |
| Matching Proteins |
|
| Site Position | 467 |
|---|---|
| MS/MS spectra | 1 [show] |
| Best localized sequence | R.DLDK#ADSMIR.L |
| Matching Proteins |
|
| Site Position | 483 |
|---|---|
| MS/MS spectra | 9 [show] |
| Best localized sequence | R.LLFNDVQTLK#DGR.H |
| Matching Proteins |
|
| Site Position | 516 |
|---|---|
| MS/MS spectra | 22 [show] |
| Best localized sequence | R.LK#AGVAAPATQVAQVTLQSVQR.R |
| Matching Proteins |
|
| Site Position | 626 |
|---|---|
| MS/MS spectra | 13 [show] |
| Best localized sequence | R.LDLQYAK#LLNSSK.A |
| Matching Proteins |
|
| Site Position | 794 |
|---|---|
| MS/MS spectra | 53 [show] |
| Best localized sequence | R.LEDLLQDAQDEK#EQLNEYK.G |
| Matching Proteins |
|
| Site Position | 1051 |
|---|---|
| MS/MS spectra | 24 [show] |
| Best localized sequence | R.IAEQQK#AQAEVEGLGK.G |
| Matching Proteins |
|
| Site Position | 1072 |
|---|---|
| MS/MS spectra | 13 [show] |
| Best localized sequence | R.LSAEAEK#VLALPEPSPAAPTLR.S |
| Matching Proteins |
|
| Site Position | 1096 |
|---|---|
| MS/MS spectra | 431 [show] |
| Best localized sequence | R.SELELTLGK#LEQVR@.S |
| Matching Proteins |
|
| Site Position | 1136 |
|---|---|
| MS/MS spectra | 137 [show] |
| Best localized sequence | R.AHEEQLK#EAQAVPATLPELEATK.A |
| Matching Proteins |
|
| Site Position | 1296 |
|---|---|
| MS/MS spectra | 29 [show] |
| Best localized sequence | R.FAK#QYINAIK.D |
| Matching Proteins |
|
| Site Position | 1303 |
|---|---|
| MS/MS spectra | 3 [show] |
| Best localized sequence | K.QYINAIK#DYELQLVTYK.A |
| Matching Proteins |
|
| Site Position | 1313 |
|---|---|
| MS/MS spectra | 45 [show] |
| Best localized sequence | K.DYELQLVTYK#AQLEPVASPAK.K |
| Matching Proteins |
|
| Site Position | 1394 |
|---|---|
| MS/MS spectra | 2 [show] |
| Best localized sequence | R.LAEVEAALEK#QR.Q |
| Matching Proteins |
|
| Site Position | 1604 |
|---|---|
| MS/MS spectra | 17 [show] |
| Best localized sequence | R.SAEAELQSK#R.A |
| Matching Proteins |
|
| Site Position | 2536 |
|---|---|
| MS/MS spectra | 1 [show] |
| Best localized sequence | R.FIEQEK#AK.L |
| Matching Proteins |
|
| Site Position | 2549 |
|---|---|
| MS/MS spectra | 1 [show] |
| Best localized sequence | K.LEQLFQDEVAK#AQQLR.E |
| Matching Proteins |
|
| Site Position | 2817 |
|---|---|
| MS/MS spectra | 8 [show] |
| Best localized sequence | K.DPYTGQQISLFQAMQK#GLIVR.E |
| Matching Proteins |
|
| Site Position | 2874 |
|---|---|
| MS/MS spectra | 13 [show] |
| Best localized sequence | R.VLADPSDDTK#GFFDPNTHENLTYLQLLER.C |
| Matching Proteins |
|
| Site Position | 2913 |
|---|---|
| MS/MS spectra | 3 [show] |
| Best localized sequence | K.AAK#GGELVYTDSEAR.D |
| Matching Proteins |
|
| Site Position | 3202 |
|---|---|
| MS/MS spectra | 52 [show] |
| Best localized sequence | R.ADAK#AYSDPSTGEPATYGELQQR.C |
| Matching Proteins |
|
| Site Position | 3270 |
|---|---|
| MS/MS spectra | 19 [show] |
| Best localized sequence | K.TPVEVPVGGFK#GR.T |
| Matching Proteins |
|
| Site Position | 3476 |
|---|---|
| MS/MS spectra | 3 [show] |
| Best localized sequence | R.DPYSGSTISLFQAMQK#GLVLR.Q |
| Matching Proteins |
|
| Site Position | 3533 |
|---|---|
| MS/MS spectra | 12 [show] |
| Best localized sequence | R.VLADPSDDTK#GFFDPNTHENLTYR@.Q |
| Matching Proteins |
|
| Site Position | 3854 |
|---|---|
| MS/MS spectra | 17 [show] |
| Best localized sequence | R.GYLNK#DTHDQLSEPSEVR.S |
| Matching Proteins |
|
| Site Position | 3913 |
|---|---|
| MS/MS spectra | 1 [show] |
| Best localized sequence | R.K#QITMEELVR.S |
| Matching Proteins |
|
| Site Position | 3946 |
|---|---|
| MS/MS spectra | 2 [show] |
| Best localized sequence | R.EGLTSIEEVTK#NLQK.F |
| Matching Proteins |
|
| Site Position | 4024 |
|---|---|
| MS/MS spectra | 1 [show] |
| Best localized sequence | R.MGIVGPEFK#DK.L |
| Matching Proteins |
|
| Site Position | 4038 |
|---|---|
| MS/MS spectra | 1 [show] |
| Best localized sequence | R.AVTGYK#DPYSGK.L |
| Matching Proteins |
|
| Site Position | 4044 |
|---|---|
| MS/MS spectra | 1 [show] |
| Best localized sequence | K.DPYSGK#LISLFQAMK.K |
| Matching Proteins |
|
| Site Position | 4091 |
|---|---|
| MS/MS spectra | 4 [show] |
| Best localized sequence | R.LPVEVAYK#R.G |
| Matching Proteins |
|
| Site Position | 4173 |
|---|---|
| MS/MS spectra | 24 [show] |
| Best localized sequence | R.VVIVDPETGK#EMSVYEAYR.K |
| Matching Proteins |
|
| Site Position | 4234 |
|---|---|
| MS/MS spectra | 20 [show] |
| Best localized sequence | R.QYDIDDAIAK#NLIDR.S |
| Matching Proteins |
|
| Site Position | 4399 |
|---|---|
| MS/MS spectra | 1 [show] |
| Best localized sequence | K.K#GWLYYEAGQR.F |
| Matching Proteins |
|
| Site Position | 4495 |
|---|---|
| MS/MS spectra | 140 [show] |
| Best localized sequence | R.LLEAAAQSTK#GYYSPYSVSGSGSTAGSR@.T |
| Matching Proteins |
|