IPI:IPI00398779.5
Protein Information
| Protein | IPI:IPI00398779.5 |
|---|---|
| Gene Symbol | PLEC1 |
| Protein Description | Isoform 4 of Plectin-1 |
| Sequence Length | 4547 |
| Mwt | 515883.685 Da |
| Sequence | MSQHQLRVPQ PEGLGRKRTS SEDNLYLAVL RASEGKKDER DRVQKKTFTK WVNKHLIKAQ RHISDLYEDL RDGHNLISLL EVLSGDSLPR EKGRMRFHKL QNVQIALDYL RHRQVKLVNI RNDDIADGNP KLTLGLIWTI ILHFQISDIQ VSGQSEDMTA KEKLLLWSQR MVEGYQGLRC DNFTSSWRDG RLFNAIIHRH KPLLIDMNKV YRQTNLENLD QAFSVAERDL GVTRLLDPED VDVPQPDEKS IITYVSSLYD AMPRVPDVQD GVRANELQLR WQEYRELVLL LLQWMRHHTA AFEERRFPSS FEEIEILWSQ FLKFKEMELP AKEADKNRSK GIYQSLEGAV QAGQLKVPPG YHPLDVEKEW GKLHVAILER EKQLRSEFER LECLQRIVTK LQMEAGLCEE QLNQADALLQ SDVRLLAAGK VPQRAGEVER DLDKADSMIR LLFNDVQTLK DGRHPQGEQM YRRVYRLHER LVAIRTEYNL RLKAGVAAPA TQVAQVTLQS VQRRPELEDS TLRYLQDLLA WVEENQHRVD GAEWGVDLPS VEAQLGSHRG LHQSIEEFRA KIERARSDEG QLSPATRGAY RDCLGRLDLQ YAKLLNSSKA RLRSLESLHS FVAAATKELM WLNEKEEEEV GFDWSDRNTN MTAKKESYSA LMRELELKEK KIKELQNAGD RLLREDHPAR PTVESFQAAL QTQWSWMLQL CCCIEAHLKE NAAYFQFFSD VREAEGQLQK LQEALRRKYS CDRSATVTRL EDLLQDAQDE KEQLNEYKGH LSGLAKRAKA VVQLKPRHPA HPMRGRLPLL AVCDYKQVEV TVHKGDECQL VGPAQPSHWK VLSSSGSEAA VPSVCFLVPP PNQEAQEAVT RLEAQHQALV TLWHQLHVDM KSLLAWQSLR RDVQLIRSWS LATFRTLKPE EQRQALHSLE LHYQAFLRDS QDAGGFGPED RLMAEREYGS CSHHYQQLLQ SLEQGAQEES RCQRCISELK DIRLQLEACE TRTVHRLRLP LDKEPARECA QRIAEQQKAQ AEVEGLGKGV ARLSAEAEKV LALPEPSPAA PTLRSELELT LGKLEQVRSL SAIYLEKLKT ISLVIRGTQG AEEVLRAHEE QLKEAQAVPA TLPELEATKA SLKKLRAQAE AQQPTFDALR DELRGAQEVG ERLQQRHGER DVEVERWRER VAQLLERWQA VLAQTDVRQR ELEQLGRQLR YYRESADPLG AWLQDARRRQ EQIQAMPLAD SQAVREQLRQ EQALLEEIER HGEKVEECQR FAKQYINAIK DYELQLVTYK AQLEPVASPA KKPKVQSGSE SVIQEYVDLR THYSELTTLT SQYIKFISET LRRMEEEERL AEQQRAEERE RLAEVEAALE KQRQLAEAHA QAKAQAEREA KELQQRMQEE VVRREEAAVD AQQQKRSIQE ELQQLRQSSE AEIQAKARQA EAAERSRLRI EEEIRVVRLQ LEATERQRGG AEGELQALRA RAEEAEAQKR QAQEEAERLR RQVQDESQRK RQAEVELASR VKAEAEAARE KQRALQALEE LRLQAEEAER RLRQAEVERA RQVQVALETA QRSAEAELQS KRASFAEKTA QLERSLQEEH VAVAQLREEA ERRAQQQAEA ERAREEAERE LERWQLKANE ALRLRLQAEE VAQQKSLAQA EAEKQKEEAE REARRRGKAE EQAVRQRELA EQELEKQRQL AEGTAQQRLA AEQELIRLRA ETEQGEQQRQ LLEEELARLQ REAAAATQKR QELEAELAKV RAEMEVLLAS KARAEEESRS TSEKSKQRLE AEAGRFRELA EEAARLRALA EEAKRQRQLA EEDAARQRAE AERVLAEKLA AIGEATRLKT EAEIALKEKE AENERLRRLA EDEAFQRRRL EEQAAQHKAD IEERLAQLRK ASDSELERQK GLVEDTLRQR RQVEEEILAL KASFEKAAAG KAELELELGR IRSNAEDTLR SKEQAELEAA RQRQLAAEEE RRRREAEERV QKSLAAEEEA ARQRKAALEE VERLKAKVEE ARRLRERAEQ ESARQLQLAQ EAAQKRLQAE EKAHAFAVQQ KEQELQQTLQ QEQSVLDQLR GEAEAARRAA EEAEEARVQA EREAAQSRRQ VEEAERLKQS AEEQAQARAQ AQAAAEKLRK EAEQEAARRA QAEQAALRQK QAADAEMEKH KKFAEQTLRQ KAQVEQELTT LRLQLEETDH QKNLLDEELQ RLKAEATEAA RQRSQVEEEL FSVRVQMEEL SKLKARIEAE NRALILRDKD NTQRFLQEEA EKMKQVAEEA ARLSVAAQEA ARLRQLAEED LAQQRALAEK MLKEKMQAVQ EATRLKAEAE LLQQQKELAQ EQARRLQEDK EQMAQQLAEE TQGFQRTLEA ERQRQLEMSA EAERLKLRVA EMSRAQARAE EDAQRFRKQA EEIGEKLHRT ELATQEKVTL VQTLEIQRQQ SDHDAERLRE AIAELEREKE KLQQEAKLLQ LKSEEMQTVQ QEQLLQETQA LQQSFLSEKD SLLQRERFIE QEKAKLEQLF QDEVAKAQQL REEQQRQQQQ MEQERQRLVA SMEEARRRQH EAEEGVRRKQ EELQQLEQQR RQQEELLAEE NQRLREQLQL LEEQHRAALA HSEEVTASQV AATKTLPNGR DALDGPAAEA EPEHSFDGLR RKVSAQRLQE AGILSAEELQ RLAQGHTTVD ELARREDVRH YLQGRSSIAG LLLKATNEKL SVYAALQRQL LSPGTALILL EAQAASGFLL DPVRNRRLTV NEAVKEGVVG PELHHKLLSA ERAVTGYKDP YTGQQISLFQ AMQKGLIVRE HGIRLLEAQI ATGGVIDPVH SHRVPVDVAY RRGYFDEEMN RVLADPSDDT KGFFDPNTHE NLTYLQLLER CVEDPETGLC LLPLTDKAAK GGELVYTDSE ARDVFEKATV SAPFGKFQGK TVTIWEIINS EYFTAEQRRD LLRQFRTGRI TVEKIIKIII TVVEEQEQKG RLCFEGLRSL VPAAELLESR VIDRELYQQL QRGERSVRDV AEVDTVRRAL RGANVIAGVW LEEAGQKLSI YNALKKDLLP SDMAVALLEA QAGTGHIIDP ATSARLTVDE AVRAGLVGPE FHEKLLSAEK AVTGYRDPYT GQSVSLFQAL KKGLIPREQG LRLLDAQLST GGIVDPSKSH RVPLDVACAR GCLDEETSRA LSAPRADAKA YSDPSTGEPA TYGELQQRCR PDQLTGLSLL PLSEKAARAR QEELYSELQA RETFEKTPVE VPVGGFKGRT VTVWELISSE YFTAEQRQEL LRQFRTGKVT VEKVIKILIT IVEEVETLRQ ERLSFSGLRA PVPASELLAS GVLSRAQFEQ LKDGKTTVKD LSELGSVRTL LQGSGCLAGI YLEDTKEKVS IYEAMRRGLL RATTAALLLE AQAATGFLVD PVRNQRLYVH EAVKAGVVGP ELHEQLLSAE KAVTGYRDPY SGSTISLFQA MQKGLVLRQH GIRLLEAQIA TGGIIDPVHS HRVPVDVAYQ RGYFSEEMNR VLADPSDDTK GFFDPNTHEN LTYRQLLERC VEDPETGLRL LPLKGAEKAE VVETTQVYTE EETRRAFEET QIDIPGGGSH GGSTMSLWEV MQSDLIPEEQ RAQLMADFQA GRVTKERMII IIIEIIEKTE IIRQQGLASY DYVRRRLTAE DLFEARIISL ETYNLLREGT RSLREALEAE SAWCYLYGTG SVAGVYLPGS RQTLSIYQAL KKGLLSAEVA RLLLEAQAAT GFLLDPVKGE RLTVDEAVRK GLVGPELHDR LLSAERAVTG YRDPYTEQTI SLFQAMKKEL IPTEEALRLL DAQLATGGIV DPRLGFHLPL EVAYQRGYLN KDTHDQLSEP SEVRSYVDPS TDERLSYTQL LRRCRRDDGT GQLLLPLSDA RKLTFRGLRK QITMEELVRS QVMDEATALQ LREGLTSIEE VTKNLQKFLE GTSCIAGVFV DATKERLSVY QAMKKGIIRP GTAFELLEAQ AATGYVIDPI KGLKLTVEEA VRMGIVGPEF KDKLLSAERA VTGYKDPYSG KLISLFQAMK KGLILKDHGI RLLEAQIATG GIIDPEESHR LPVEVAYKRG LFDEEMNEIL TDPSDDTKGF FDPNTEENLT YLQLMERCIT DPQTGLCLLP LKEKKRERKT SSKSSVRKRR VVIVDPETGK EMSVYEAYRK GLIDHQTYLE LSEQECEWEE ITISSSDGVV KSMIIDRRSG RQYDIDDAIA KNLIDRSALD QYRAGTLSIT EFADMLSGNA GGFRSRSSSV GSSSSYPISP AVSRTQLASW SDPTEETGPV AGILDTETLE KVSITEAMHR NLVDNITGQR LLEAQACTGG IIDPSTGERF PVTDAVNKGL VDKIMVDRIN LAQKAFCGFE DPRTKTKMSA AQALKKGWLY YEAGQRFLEV QYLTGGLIEP DTPGRVPLDE ALQRGTVDAR TAQKLRDVGA YSKYLTCPKT KLKISYKDAL DRSMVEEGTG LRLLEAAAQS TKGYYSPYSV SGSGSTAGSR TGSRTGSRAG SRRGSFDATG SGFSMTFSSS SYSSSGYGRR YASGSSASLG GPESAVA |
Modification Site Information
| Site Position | 332 |
|---|---|
| MS/MS spectra | 14 [show] |
| Best localized sequence | K.EMELPAK#EADK.N |
| Matching Proteins |
|
| Site Position | 340 |
|---|---|
| MS/MS spectra | 2 [show] |
| Best localized sequence | R.SK#GIYQSLEGAVQAGQLK.V |
| Matching Proteins |
|
| Site Position | 356 |
|---|---|
| MS/MS spectra | 8 [show] |
| Best localized sequence | K.GIYQSLEGAVQAGQLK#VPPGYHPLDVEK.E |
| Matching Proteins |
|
| Site Position | 444 |
|---|---|
| MS/MS spectra | 1 [show] |
| Best localized sequence | R.DLDK#ADSMIR.L |
| Matching Proteins |
|
| Site Position | 460 |
|---|---|
| MS/MS spectra | 9 [show] |
| Best localized sequence | R.LLFNDVQTLK#DGR.H |
| Matching Proteins |
|
| Site Position | 493 |
|---|---|
| MS/MS spectra | 22 [show] |
| Best localized sequence | R.LK#AGVAAPATQVAQVTLQSVQR.R |
| Matching Proteins |
|
| Site Position | 603 |
|---|---|
| MS/MS spectra | 13 [show] |
| Best localized sequence | R.LDLQYAK#LLNSSK.A |
| Matching Proteins |
|
| Site Position | 771 |
|---|---|
| MS/MS spectra | 53 [show] |
| Best localized sequence | R.LEDLLQDAQDEK#EQLNEYK.G |
| Matching Proteins |
|
| Site Position | 1028 |
|---|---|
| MS/MS spectra | 24 [show] |
| Best localized sequence | R.IAEQQK#AQAEVEGLGK.G |
| Matching Proteins |
|
| Site Position | 1049 |
|---|---|
| MS/MS spectra | 13 [show] |
| Best localized sequence | R.LSAEAEK#VLALPEPSPAAPTLR.S |
| Matching Proteins |
|
| Site Position | 1073 |
|---|---|
| MS/MS spectra | 431 [show] |
| Best localized sequence | R.SELELTLGK#LEQVR@.S |
| Matching Proteins |
|
| Site Position | 1113 |
|---|---|
| MS/MS spectra | 137 [show] |
| Best localized sequence | R.AHEEQLK#EAQAVPATLPELEATK.A |
| Matching Proteins |
|
| Site Position | 1273 |
|---|---|
| MS/MS spectra | 29 [show] |
| Best localized sequence | R.FAK#QYINAIK.D |
| Matching Proteins |
|
| Site Position | 1280 |
|---|---|
| MS/MS spectra | 3 [show] |
| Best localized sequence | K.QYINAIK#DYELQLVTYK.A |
| Matching Proteins |
|
| Site Position | 1290 |
|---|---|
| MS/MS spectra | 45 [show] |
| Best localized sequence | K.DYELQLVTYK#AQLEPVASPAK.K |
| Matching Proteins |
|
| Site Position | 1371 |
|---|---|
| MS/MS spectra | 2 [show] |
| Best localized sequence | R.LAEVEAALEK#QR.Q |
| Matching Proteins |
|
| Site Position | 1581 |
|---|---|
| MS/MS spectra | 17 [show] |
| Best localized sequence | R.SAEAELQSK#R.A |
| Matching Proteins |
|
| Site Position | 2513 |
|---|---|
| MS/MS spectra | 1 [show] |
| Best localized sequence | R.FIEQEK#AK.L |
| Matching Proteins |
|
| Site Position | 2526 |
|---|---|
| MS/MS spectra | 1 [show] |
| Best localized sequence | K.LEQLFQDEVAK#AQQLR.E |
| Matching Proteins |
|
| Site Position | 2794 |
|---|---|
| MS/MS spectra | 8 [show] |
| Best localized sequence | K.DPYTGQQISLFQAMQK#GLIVR.E |
| Matching Proteins |
|
| Site Position | 2851 |
|---|---|
| MS/MS spectra | 13 [show] |
| Best localized sequence | R.VLADPSDDTK#GFFDPNTHENLTYLQLLER.C |
| Matching Proteins |
|
| Site Position | 2890 |
|---|---|
| MS/MS spectra | 3 [show] |
| Best localized sequence | K.AAK#GGELVYTDSEAR.D |
| Matching Proteins |
|
| Site Position | 3179 |
|---|---|
| MS/MS spectra | 52 [show] |
| Best localized sequence | R.ADAK#AYSDPSTGEPATYGELQQR.C |
| Matching Proteins |
|
| Site Position | 3247 |
|---|---|
| MS/MS spectra | 19 [show] |
| Best localized sequence | K.TPVEVPVGGFK#GR.T |
| Matching Proteins |
|
| Site Position | 3453 |
|---|---|
| MS/MS spectra | 3 [show] |
| Best localized sequence | R.DPYSGSTISLFQAMQK#GLVLR.Q |
| Matching Proteins |
|
| Site Position | 3510 |
|---|---|
| MS/MS spectra | 12 [show] |
| Best localized sequence | R.VLADPSDDTK#GFFDPNTHENLTYR@.Q |
| Matching Proteins |
|
| Site Position | 3831 |
|---|---|
| MS/MS spectra | 17 [show] |
| Best localized sequence | R.GYLNK#DTHDQLSEPSEVR.S |
| Matching Proteins |
|
| Site Position | 3890 |
|---|---|
| MS/MS spectra | 1 [show] |
| Best localized sequence | R.K#QITMEELVR.S |
| Matching Proteins |
|
| Site Position | 3923 |
|---|---|
| MS/MS spectra | 2 [show] |
| Best localized sequence | R.EGLTSIEEVTK#NLQK.F |
| Matching Proteins |
|
| Site Position | 4001 |
|---|---|
| MS/MS spectra | 1 [show] |
| Best localized sequence | R.MGIVGPEFK#DK.L |
| Matching Proteins |
|
| Site Position | 4015 |
|---|---|
| MS/MS spectra | 1 [show] |
| Best localized sequence | R.AVTGYK#DPYSGK.L |
| Matching Proteins |
|
| Site Position | 4021 |
|---|---|
| MS/MS spectra | 1 [show] |
| Best localized sequence | K.DPYSGK#LISLFQAMK.K |
| Matching Proteins |
|
| Site Position | 4068 |
|---|---|
| MS/MS spectra | 4 [show] |
| Best localized sequence | R.LPVEVAYK#R.G |
| Matching Proteins |
|
| Site Position | 4150 |
|---|---|
| MS/MS spectra | 24 [show] |
| Best localized sequence | R.VVIVDPETGK#EMSVYEAYR.K |
| Matching Proteins |
|
| Site Position | 4211 |
|---|---|
| MS/MS spectra | 20 [show] |
| Best localized sequence | R.QYDIDDAIAK#NLIDR.S |
| Matching Proteins |
|
| Site Position | 4376 |
|---|---|
| MS/MS spectra | 1 [show] |
| Best localized sequence | K.K#GWLYYEAGQR.F |
| Matching Proteins |
|
| Site Position | 4472 |
|---|---|
| MS/MS spectra | 140 [show] |
| Best localized sequence | R.LLEAAAQSTK#GYYSPYSVSGSGSTAGSR@.T |
| Matching Proteins |
|