IPI:IPI00398778.3
Protein Information
| Protein | IPI:IPI00398778.3 |
|---|---|
| Gene Symbol | PLEC1 |
| Protein Description | Isoform 6 of Plectin-1 |
| Sequence Length | 4551 |
| Mwt | 516163.567 Da |
| Sequence | MSGAGGAFAS PREVLLERPC WLDGGCEPAR RGYLYQQLCC VDERDRVQKK TFTKWVNKHL IKAQRHISDL YEDLRDGHNL ISLLEVLSGD SLPREKGRMR FHKLQNVQIA LDYLRHRQVK LVNIRNDDIA DGNPKLTLGL IWTIILHFQI SDIQVSGQSE DMTAKEKLLL WSQRMVEGYQ GLRCDNFTSS WRDGRLFNAI IHRHKPLLID MNKVYRQTNL ENLDQAFSVA ERDLGVTRLL DPEDVDVPQP DEKSIITYVS SLYDAMPRVP DVQDGVRANE LQLRWQEYRE LVLLLLQWMR HHTAAFEERR FPSSFEEIEI LWSQFLKFKE MELPAKEADK NRSKGIYQSL EGAVQAGQLK VPPGYHPLDV EKEWGKLHVA ILEREKQLRS EFERLECLQR IVTKLQMEAG LCEEQLNQAD ALLQSDVRLL AAGKVPQRAG EVERDLDKAD SMIRLLFNDV QTLKDGRHPQ GEQMYRRVYR LHERLVAIRT EYNLRLKAGV AAPATQVAQV TLQSVQRRPE LEDSTLRYLQ DLLAWVEENQ HRVDGAEWGV DLPSVEAQLG SHRGLHQSIE EFRAKIERAR SDEGQLSPAT RGAYRDCLGR LDLQYAKLLN SSKARLRSLE SLHSFVAAAT KELMWLNEKE EEEVGFDWSD RNTNMTAKKE SYSALMRELE LKEKKIKELQ NAGDRLLRED HPARPTVESF QAALQTQWSW MLQLCCCIEA HLKENAAYFQ FFSDVREAEG QLQKLQEALR RKYSCDRSAT VTRLEDLLQD AQDEKEQLNE YKGHLSGLAK RAKAVVQLKP RHPAHPMRGR LPLLAVCDYK QVEVTVHKGD ECQLVGPAQP SHWKVLSSSG SEAAVPSVCF LVPPPNQEAQ EAVTRLEAQH QALVTLWHQL HVDMKSLLAW QSLRRDVQLI RSWSLATFRT LKPEEQRQAL HSLELHYQAF LRDSQDAGGF GPEDRLMAER EYGSCSHHYQ QLLQSLEQGA QEESRCQRCI SELKDIRLQL EACETRTVHR LRLPLDKEPA RECAQRIAEQ QKAQAEVEGL GKGVARLSAE AEKVLALPEP SPAAPTLRSE LELTLGKLEQ VRSLSAIYLE KLKTISLVIR GTQGAEEVLR AHEEQLKEAQ AVPATLPELE ATKASLKKLR AQAEAQQPTF DALRDELRGA QEVGERLQQR HGERDVEVER WRERVAQLLE RWQAVLAQTD VRQRELEQLG RQLRYYRESA DPLGAWLQDA RRRQEQIQAM PLADSQAVRE QLRQEQALLE EIERHGEKVE ECQRFAKQYI NAIKDYELQL VTYKAQLEPV ASPAKKPKVQ SGSESVIQEY VDLRTHYSEL TTLTSQYIKF ISETLRRMEE EERLAEQQRA EERERLAEVE AALEKQRQLA EAHAQAKAQA EREAKELQQR MQEEVVRREE AAVDAQQQKR SIQEELQQLR QSSEAEIQAK ARQAEAAERS RLRIEEEIRV VRLQLEATER QRGGAEGELQ ALRARAEEAE AQKRQAQEEA ERLRRQVQDE SQRKRQAEVE LASRVKAEAE AAREKQRALQ ALEELRLQAE EAERRLRQAE VERARQVQVA LETAQRSAEA ELQSKRASFA EKTAQLERSL QEEHVAVAQL REEAERRAQQ QAEAERAREE AERELERWQL KANEALRLRL QAEEVAQQKS LAQAEAEKQK EEAEREARRR GKAEEQAVRQ RELAEQELEK QRQLAEGTAQ QRLAAEQELI RLRAETEQGE QQRQLLEEEL ARLQREAAAA TQKRQELEAE LAKVRAEMEV LLASKARAEE ESRSTSEKSK QRLEAEAGRF RELAEEAARL RALAEEAKRQ RQLAEEDAAR QRAEAERVLA EKLAAIGEAT RLKTEAEIAL KEKEAENERL RRLAEDEAFQ RRRLEEQAAQ HKADIEERLA QLRKASDSEL ERQKGLVEDT LRQRRQVEEE ILALKASFEK AAAGKAELEL ELGRIRSNAE DTLRSKEQAE LEAARQRQLA AEEERRRREA EERVQKSLAA EEEAARQRKA ALEEVERLKA KVEEARRLRE RAEQESARQL QLAQEAAQKR LQAEEKAHAF AVQQKEQELQ QTLQQEQSVL DQLRGEAEAA RRAAEEAEEA RVQAEREAAQ SRRQVEEAER LKQSAEEQAQ ARAQAQAAAE KLRKEAEQEA ARRAQAEQAA LRQKQAADAE MEKHKKFAEQ TLRQKAQVEQ ELTTLRLQLE ETDHQKNLLD EELQRLKAEA TEAARQRSQV EEELFSVRVQ MEELSKLKAR IEAENRALIL RDKDNTQRFL QEEAEKMKQV AEEAARLSVA AQEAARLRQL AEEDLAQQRA LAEKMLKEKM QAVQEATRLK AEAELLQQQK ELAQEQARRL QEDKEQMAQQ LAEETQGFQR TLEAERQRQL EMSAEAERLK LRVAEMSRAQ ARAEEDAQRF RKQAEEIGEK LHRTELATQE KVTLVQTLEI QRQQSDHDAE RLREAIAELE REKEKLQQEA KLLQLKSEEM QTVQQEQLLQ ETQALQQSFL SEKDSLLQRE RFIEQEKAKL EQLFQDEVAK AQQLREEQQR QQQQMEQERQ RLVASMEEAR RRQHEAEEGV RRKQEELQQL EQQRRQQEEL LAEENQRLRE QLQLLEEQHR AALAHSEEVT ASQVAATKTL PNGRDALDGP AAEAEPEHSF DGLRRKVSAQ RLQEAGILSA EELQRLAQGH TTVDELARRE DVRHYLQGRS SIAGLLLKAT NEKLSVYAAL QRQLLSPGTA LILLEAQAAS GFLLDPVRNR RLTVNEAVKE GVVGPELHHK LLSAERAVTG YKDPYTGQQI SLFQAMQKGL IVREHGIRLL EAQIATGGVI DPVHSHRVPV DVAYRRGYFD EEMNRVLADP SDDTKGFFDP NTHENLTYLQ LLERCVEDPE TGLCLLPLTD KAAKGGELVY TDSEARDVFE KATVSAPFGK FQGKTVTIWE IINSEYFTAE QRRDLLRQFR TGRITVEKII KIIITVVEEQ EQKGRLCFEG LRSLVPAAEL LESRVIDREL YQQLQRGERS VRDVAEVDTV RRALRGANVI AGVWLEEAGQ KLSIYNALKK DLLPSDMAVA LLEAQAGTGH IIDPATSARL TVDEAVRAGL VGPEFHEKLL SAEKAVTGYR DPYTGQSVSL FQALKKGLIP REQGLRLLDA QLSTGGIVDP SKSHRVPLDV ACARGCLDEE TSRALSAPRA DAKAYSDPST GEPATYGELQ QRCRPDQLTG LSLLPLSEKA ARARQEELYS ELQARETFEK TPVEVPVGGF KGRTVTVWEL ISSEYFTAEQ RQELLRQFRT GKVTVEKVIK ILITIVEEVE TLRQERLSFS GLRAPVPASE LLASGVLSRA QFEQLKDGKT TVKDLSELGS VRTLLQGSGC LAGIYLEDTK EKVSIYEAMR RGLLRATTAA LLLEAQAATG FLVDPVRNQR LYVHEAVKAG VVGPELHEQL LSAEKAVTGY RDPYSGSTIS LFQAMQKGLV LRQHGIRLLE AQIATGGIID PVHSHRVPVD VAYQRGYFSE EMNRVLADPS DDTKGFFDPN THENLTYRQL LERCVEDPET GLRLLPLKGA EKAEVVETTQ VYTEEETRRA FEETQIDIPG GGSHGGSTMS LWEVMQSDLI PEEQRAQLMA DFQAGRVTKE RMIIIIIEII EKTEIIRQQG LASYDYVRRR LTAEDLFEAR IISLETYNLL REGTRSLREA LEAESAWCYL YGTGSVAGVY LPGSRQTLSI YQALKKGLLS AEVARLLLEA QAATGFLLDP VKGERLTVDE AVRKGLVGPE LHDRLLSAER AVTGYRDPYT EQTISLFQAM KKELIPTEEA LRLLDAQLAT GGIVDPRLGF HLPLEVAYQR GYLNKDTHDQ LSEPSEVRSY VDPSTDERLS YTQLLRRCRR DDGTGQLLLP LSDARKLTFR GLRKQITMEE LVRSQVMDEA TALQLREGLT SIEEVTKNLQ KFLEGTSCIA GVFVDATKER LSVYQAMKKG IIRPGTAFEL LEAQAATGYV IDPIKGLKLT VEEAVRMGIV GPEFKDKLLS AERAVTGYKD PYSGKLISLF QAMKKGLILK DHGIRLLEAQ IATGGIIDPE ESHRLPVEVA YKRGLFDEEM NEILTDPSDD TKGFFDPNTE ENLTYLQLME RCITDPQTGL CLLPLKEKKR ERKTSSKSSV RKRRVVIVDP ETGKEMSVYE AYRKGLIDHQ TYLELSEQEC EWEEITISSS DGVVKSMIID RRSGRQYDID DAIAKNLIDR SALDQYRAGT LSITEFADML SGNAGGFRSR SSSVGSSSSY PISPAVSRTQ LASWSDPTEE TGPVAGILDT ETLEKVSITE AMHRNLVDNI TGQRLLEAQA CTGGIIDPST GERFPVTDAV NKGLVDKIMV DRINLAQKAF CGFEDPRTKT KMSAAQALKK GWLYYEAGQR FLEVQYLTGG LIEPDTPGRV PLDEALQRGT VDARTAQKLR DVGAYSKYLT CPKTKLKISY KDALDRSMVE EGTGLRLLEA AAQSTKGYYS PYSVSGSGST AGSRTGSRTG SRAGSRRGSF DATGSGFSMT FSSSSYSSSG YGRRYASGSS ASLGGPESAV A |
Modification Site Information
| Site Position | 336 |
|---|---|
| MS/MS spectra | 14 [show] |
| Best localized sequence | K.EMELPAK#EADK.N |
| Matching Proteins |
|
| Site Position | 344 |
|---|---|
| MS/MS spectra | 2 [show] |
| Best localized sequence | R.SK#GIYQSLEGAVQAGQLK.V |
| Matching Proteins |
|
| Site Position | 360 |
|---|---|
| MS/MS spectra | 8 [show] |
| Best localized sequence | K.GIYQSLEGAVQAGQLK#VPPGYHPLDVEK.E |
| Matching Proteins |
|
| Site Position | 448 |
|---|---|
| MS/MS spectra | 1 [show] |
| Best localized sequence | R.DLDK#ADSMIR.L |
| Matching Proteins |
|
| Site Position | 464 |
|---|---|
| MS/MS spectra | 9 [show] |
| Best localized sequence | R.LLFNDVQTLK#DGR.H |
| Matching Proteins |
|
| Site Position | 497 |
|---|---|
| MS/MS spectra | 22 [show] |
| Best localized sequence | R.LK#AGVAAPATQVAQVTLQSVQR.R |
| Matching Proteins |
|
| Site Position | 607 |
|---|---|
| MS/MS spectra | 13 [show] |
| Best localized sequence | R.LDLQYAK#LLNSSK.A |
| Matching Proteins |
|
| Site Position | 775 |
|---|---|
| MS/MS spectra | 53 [show] |
| Best localized sequence | R.LEDLLQDAQDEK#EQLNEYK.G |
| Matching Proteins |
|
| Site Position | 1032 |
|---|---|
| MS/MS spectra | 24 [show] |
| Best localized sequence | R.IAEQQK#AQAEVEGLGK.G |
| Matching Proteins |
|
| Site Position | 1053 |
|---|---|
| MS/MS spectra | 13 [show] |
| Best localized sequence | R.LSAEAEK#VLALPEPSPAAPTLR.S |
| Matching Proteins |
|
| Site Position | 1077 |
|---|---|
| MS/MS spectra | 431 [show] |
| Best localized sequence | R.SELELTLGK#LEQVR@.S |
| Matching Proteins |
|
| Site Position | 1117 |
|---|---|
| MS/MS spectra | 137 [show] |
| Best localized sequence | R.AHEEQLK#EAQAVPATLPELEATK.A |
| Matching Proteins |
|
| Site Position | 1277 |
|---|---|
| MS/MS spectra | 29 [show] |
| Best localized sequence | R.FAK#QYINAIK.D |
| Matching Proteins |
|
| Site Position | 1284 |
|---|---|
| MS/MS spectra | 3 [show] |
| Best localized sequence | K.QYINAIK#DYELQLVTYK.A |
| Matching Proteins |
|
| Site Position | 1294 |
|---|---|
| MS/MS spectra | 45 [show] |
| Best localized sequence | K.DYELQLVTYK#AQLEPVASPAK.K |
| Matching Proteins |
|
| Site Position | 1375 |
|---|---|
| MS/MS spectra | 2 [show] |
| Best localized sequence | R.LAEVEAALEK#QR.Q |
| Matching Proteins |
|
| Site Position | 1585 |
|---|---|
| MS/MS spectra | 17 [show] |
| Best localized sequence | R.SAEAELQSK#R.A |
| Matching Proteins |
|
| Site Position | 2517 |
|---|---|
| MS/MS spectra | 1 [show] |
| Best localized sequence | R.FIEQEK#AK.L |
| Matching Proteins |
|
| Site Position | 2530 |
|---|---|
| MS/MS spectra | 1 [show] |
| Best localized sequence | K.LEQLFQDEVAK#AQQLR.E |
| Matching Proteins |
|
| Site Position | 2798 |
|---|---|
| MS/MS spectra | 8 [show] |
| Best localized sequence | K.DPYTGQQISLFQAMQK#GLIVR.E |
| Matching Proteins |
|
| Site Position | 2855 |
|---|---|
| MS/MS spectra | 13 [show] |
| Best localized sequence | R.VLADPSDDTK#GFFDPNTHENLTYLQLLER.C |
| Matching Proteins |
|
| Site Position | 2894 |
|---|---|
| MS/MS spectra | 3 [show] |
| Best localized sequence | K.AAK#GGELVYTDSEAR.D |
| Matching Proteins |
|
| Site Position | 3183 |
|---|---|
| MS/MS spectra | 52 [show] |
| Best localized sequence | R.ADAK#AYSDPSTGEPATYGELQQR.C |
| Matching Proteins |
|
| Site Position | 3251 |
|---|---|
| MS/MS spectra | 19 [show] |
| Best localized sequence | K.TPVEVPVGGFK#GR.T |
| Matching Proteins |
|
| Site Position | 3457 |
|---|---|
| MS/MS spectra | 3 [show] |
| Best localized sequence | R.DPYSGSTISLFQAMQK#GLVLR.Q |
| Matching Proteins |
|
| Site Position | 3514 |
|---|---|
| MS/MS spectra | 12 [show] |
| Best localized sequence | R.VLADPSDDTK#GFFDPNTHENLTYR@.Q |
| Matching Proteins |
|
| Site Position | 3835 |
|---|---|
| MS/MS spectra | 17 [show] |
| Best localized sequence | R.GYLNK#DTHDQLSEPSEVR.S |
| Matching Proteins |
|
| Site Position | 3894 |
|---|---|
| MS/MS spectra | 1 [show] |
| Best localized sequence | R.K#QITMEELVR.S |
| Matching Proteins |
|
| Site Position | 3927 |
|---|---|
| MS/MS spectra | 2 [show] |
| Best localized sequence | R.EGLTSIEEVTK#NLQK.F |
| Matching Proteins |
|
| Site Position | 4005 |
|---|---|
| MS/MS spectra | 1 [show] |
| Best localized sequence | R.MGIVGPEFK#DK.L |
| Matching Proteins |
|
| Site Position | 4019 |
|---|---|
| MS/MS spectra | 1 [show] |
| Best localized sequence | R.AVTGYK#DPYSGK.L |
| Matching Proteins |
|
| Site Position | 4025 |
|---|---|
| MS/MS spectra | 1 [show] |
| Best localized sequence | K.DPYSGK#LISLFQAMK.K |
| Matching Proteins |
|
| Site Position | 4072 |
|---|---|
| MS/MS spectra | 4 [show] |
| Best localized sequence | R.LPVEVAYK#R.G |
| Matching Proteins |
|
| Site Position | 4154 |
|---|---|
| MS/MS spectra | 24 [show] |
| Best localized sequence | R.VVIVDPETGK#EMSVYEAYR.K |
| Matching Proteins |
|
| Site Position | 4215 |
|---|---|
| MS/MS spectra | 20 [show] |
| Best localized sequence | R.QYDIDDAIAK#NLIDR.S |
| Matching Proteins |
|
| Site Position | 4380 |
|---|---|
| MS/MS spectra | 1 [show] |
| Best localized sequence | K.K#GWLYYEAGQR.F |
| Matching Proteins |
|
| Site Position | 4476 |
|---|---|
| MS/MS spectra | 140 [show] |
| Best localized sequence | R.LLEAAAQSTK#GYYSPYSVSGSGSTAGSR@.T |
| Matching Proteins |
|