IPI:IPI00420096.4
Protein Information
| Protein | IPI:IPI00420096.4 |
|---|---|
| Gene Symbol | PLEC1 |
| Protein Description | Isoform 8 of Plectin-1 |
| Sequence Length | 4525 |
| Mwt | 513393.328 Da |
| Sequence | MDPSRAIQNE ISSLKDERDR VQKKTFTKWV NKHLIKAQRH ISDLYEDLRD GHNLISLLEV LSGDSLPREK GRMRFHKLQN VQIALDYLRH RQVKLVNIRN DDIADGNPKL TLGLIWTIIL HFQISDIQVS GQSEDMTAKE KLLLWSQRMV EGYQGLRCDN FTSSWRDGRL FNAIIHRHKP LLIDMNKVYR QTNLENLDQA FSVAERDLGV TRLLDPEDVD VPQPDEKSII TYVSSLYDAM PRVPDVQDGV RANELQLRWQ EYRELVLLLL QWMRHHTAAF EERRFPSSFE EIEILWSQFL KFKEMELPAK EADKNRSKGI YQSLEGAVQA GQLKVPPGYH PLDVEKEWGK LHVAILEREK QLRSEFERLE CLQRIVTKLQ MEAGLCEEQL NQADALLQSD VRLLAAGKVP QRAGEVERDL DKADSMIRLL FNDVQTLKDG RHPQGEQMYR RVYRLHERLV AIRTEYNLRL KAGVAAPATQ VAQVTLQSVQ RRPELEDSTL RYLQDLLAWV EENQHRVDGA EWGVDLPSVE AQLGSHRGLH QSIEEFRAKI ERARSDEGQL SPATRGAYRD CLGRLDLQYA KLLNSSKARL RSLESLHSFV AAATKELMWL NEKEEEEVGF DWSDRNTNMT AKKESYSALM RELELKEKKI KELQNAGDRL LREDHPARPT VESFQAALQT QWSWMLQLCC CIEAHLKENA AYFQFFSDVR EAEGQLQKLQ EALRRKYSCD RSATVTRLED LLQDAQDEKE QLNEYKGHLS GLAKRAKAVV QLKPRHPAHP MRGRLPLLAV CDYKQVEVTV HKGDECQLVG PAQPSHWKVL SSSGSEAAVP SVCFLVPPPN QEAQEAVTRL EAQHQALVTL WHQLHVDMKS LLAWQSLRRD VQLIRSWSLA TFRTLKPEEQ RQALHSLELH YQAFLRDSQD AGGFGPEDRL MAEREYGSCS HHYQQLLQSL EQGAQEESRC QRCISELKDI RLQLEACETR TVHRLRLPLD KEPARECAQR IAEQQKAQAE VEGLGKGVAR LSAEAEKVLA LPEPSPAAPT LRSELELTLG KLEQVRSLSA IYLEKLKTIS LVIRGTQGAE EVLRAHEEQL KEAQAVPATL PELEATKASL KKLRAQAEAQ QPTFDALRDE LRGAQEVGER LQQRHGERDV EVERWRERVA QLLERWQAVL AQTDVRQREL EQLGRQLRYY RESADPLGAW LQDARRRQEQ IQAMPLADSQ AVREQLRQEQ ALLEEIERHG EKVEECQRFA KQYINAIKDY ELQLVTYKAQ LEPVASPAKK PKVQSGSESV IQEYVDLRTH YSELTTLTSQ YIKFISETLR RMEEEERLAE QQRAEERERL AEVEAALEKQ RQLAEAHAQA KAQAEREAKE LQQRMQEEVV RREEAAVDAQ QQKRSIQEEL QQLRQSSEAE IQAKARQAEA AERSRLRIEE EIRVVRLQLE ATERQRGGAE GELQALRARA EEAEAQKRQA QEEAERLRRQ VQDESQRKRQ AEVELASRVK AEAEAAREKQ RALQALEELR LQAEEAERRL RQAEVERARQ VQVALETAQR SAEAELQSKR ASFAEKTAQL ERSLQEEHVA VAQLREEAER RAQQQAEAER AREEAERELE RWQLKANEAL RLRLQAEEVA QQKSLAQAEA EKQKEEAERE ARRRGKAEEQ AVRQRELAEQ ELEKQRQLAE GTAQQRLAAE QELIRLRAET EQGEQQRQLL EEELARLQRE AAAATQKRQE LEAELAKVRA EMEVLLASKA RAEEESRSTS EKSKQRLEAE AGRFRELAEE AARLRALAEE AKRQRQLAEE DAARQRAEAE RVLAEKLAAI GEATRLKTEA EIALKEKEAE NERLRRLAED EAFQRRRLEE QAAQHKADIE ERLAQLRKAS DSELERQKGL VEDTLRQRRQ VEEEILALKA SFEKAAAGKA ELELELGRIR SNAEDTLRSK EQAELEAARQ RQLAAEEERR RREAEERVQK SLAAEEEAAR QRKAALEEVE RLKAKVEEAR RLRERAEQES ARQLQLAQEA AQKRLQAEEK AHAFAVQQKE QELQQTLQQE QSVLDQLRGE AEAARRAAEE AEEARVQAER EAAQSRRQVE EAERLKQSAE EQAQARAQAQ AAAEKLRKEA EQEAARRAQA EQAALRQKQA ADAEMEKHKK FAEQTLRQKA QVEQELTTLR LQLEETDHQK NLLDEELQRL KAEATEAARQ RSQVEEELFS VRVQMEELSK LKARIEAENR ALILRDKDNT QRFLQEEAEK MKQVAEEAAR LSVAAQEAAR LRQLAEEDLA QQRALAEKML KEKMQAVQEA TRLKAEAELL QQQKELAQEQ ARRLQEDKEQ MAQQLAEETQ GFQRTLEAER QRQLEMSAEA ERLKLRVAEM SRAQARAEED AQRFRKQAEE IGEKLHRTEL ATQEKVTLVQ TLEIQRQQSD HDAERLREAI AELEREKEKL QQEAKLLQLK SEEMQTVQQE QLLQETQALQ QSFLSEKDSL LQRERFIEQE KAKLEQLFQD EVAKAQQLRE EQQRQQQQME QERQRLVASM EEARRRQHEA EEGVRRKQEE LQQLEQQRRQ QEELLAEENQ RLREQLQLLE EQHRAALAHS EEVTASQVAA TKTLPNGRDA LDGPAAEAEP EHSFDGLRRK VSAQRLQEAG ILSAEELQRL AQGHTTVDEL ARREDVRHYL QGRSSIAGLL LKATNEKLSV YAALQRQLLS PGTALILLEA QAASGFLLDP VRNRRLTVNE AVKEGVVGPE LHHKLLSAER AVTGYKDPYT GQQISLFQAM QKGLIVREHG IRLLEAQIAT GGVIDPVHSH RVPVDVAYRR GYFDEEMNRV LADPSDDTKG FFDPNTHENL TYLQLLERCV EDPETGLCLL PLTDKAAKGG ELVYTDSEAR DVFEKATVSA PFGKFQGKTV TIWEIINSEY FTAEQRRDLL RQFRTGRITV EKIIKIIITV VEEQEQKGRL CFEGLRSLVP AAELLESRVI DRELYQQLQR GERSVRDVAE VDTVRRALRG ANVIAGVWLE EAGQKLSIYN ALKKDLLPSD MAVALLEAQA GTGHIIDPAT SARLTVDEAV RAGLVGPEFH EKLLSAEKAV TGYRDPYTGQ SVSLFQALKK GLIPREQGLR LLDAQLSTGG IVDPSKSHRV PLDVACARGC LDEETSRALS APRADAKAYS DPSTGEPATY GELQQRCRPD QLTGLSLLPL SEKAARARQE ELYSELQARE TFEKTPVEVP VGGFKGRTVT VWELISSEYF TAEQRQELLR QFRTGKVTVE KVIKILITIV EEVETLRQER LSFSGLRAPV PASELLASGV LSRAQFEQLK DGKTTVKDLS ELGSVRTLLQ GSGCLAGIYL EDTKEKVSIY EAMRRGLLRA TTAALLLEAQ AATGFLVDPV RNQRLYVHEA VKAGVVGPEL HEQLLSAEKA VTGYRDPYSG STISLFQAMQ KGLVLRQHGI RLLEAQIATG GIIDPVHSHR VPVDVAYQRG YFSEEMNRVL ADPSDDTKGF FDPNTHENLT YRQLLERCVE DPETGLRLLP LKGAEKAEVV ETTQVYTEEE TRRAFEETQI DIPGGGSHGG STMSLWEVMQ SDLIPEEQRA QLMADFQAGR VTKERMIIII IEIIEKTEII RQQGLASYDY VRRRLTAEDL FEARIISLET YNLLREGTRS LREALEAESA WCYLYGTGSV AGVYLPGSRQ TLSIYQALKK GLLSAEVARL LLEAQAATGF LLDPVKGERL TVDEAVRKGL VGPELHDRLL SAERAVTGYR DPYTEQTISL FQAMKKELIP TEEALRLLDA QLATGGIVDP RLGFHLPLEV AYQRGYLNKD THDQLSEPSE VRSYVDPSTD ERLSYTQLLR RCRRDDGTGQ LLLPLSDARK LTFRGLRKQI TMEELVRSQV MDEATALQLR EGLTSIEEVT KNLQKFLEGT SCIAGVFVDA TKERLSVYQA MKKGIIRPGT AFELLEAQAA TGYVIDPIKG LKLTVEEAVR MGIVGPEFKD KLLSAERAVT GYKDPYSGKL ISLFQAMKKG LILKDHGIRL LEAQIATGGI IDPEESHRLP VEVAYKRGLF DEEMNEILTD PSDDTKGFFD PNTEENLTYL QLMERCITDP QTGLCLLPLK EKKRERKTSS KSSVRKRRVV IVDPETGKEM SVYEAYRKGL IDHQTYLELS EQECEWEEIT ISSSDGVVKS MIIDRRSGRQ YDIDDAIAKN LIDRSALDQY RAGTLSITEF ADMLSGNAGG FRSRSSSVGS SSSYPISPAV SRTQLASWSD PTEETGPVAG ILDTETLEKV SITEAMHRNL VDNITGQRLL EAQACTGGII DPSTGERFPV TDAVNKGLVD KIMVDRINLA QKAFCGFEDP RTKTKMSAAQ ALKKGWLYYE AGQRFLEVQY LTGGLIEPDT PGRVPLDEAL QRGTVDARTA QKLRDVGAYS KYLTCPKTKL KISYKDALDR SMVEEGTGLR LLEAAAQSTK GYYSPYSVSG SGSTAGSRTG SRTGSRAGSR RGSFDATGSG FSMTFSSSSY SSSGYGRRYA SGSSASLGGP ESAVA |
Modification Site Information
| Site Position | 310 |
|---|---|
| MS/MS spectra | 14 [show] |
| Best localized sequence | K.EMELPAK#EADK.N |
| Matching Proteins |
|
| Site Position | 318 |
|---|---|
| MS/MS spectra | 2 [show] |
| Best localized sequence | R.SK#GIYQSLEGAVQAGQLK.V |
| Matching Proteins |
|
| Site Position | 334 |
|---|---|
| MS/MS spectra | 8 [show] |
| Best localized sequence | K.GIYQSLEGAVQAGQLK#VPPGYHPLDVEK.E |
| Matching Proteins |
|
| Site Position | 422 |
|---|---|
| MS/MS spectra | 1 [show] |
| Best localized sequence | R.DLDK#ADSMIR.L |
| Matching Proteins |
|
| Site Position | 438 |
|---|---|
| MS/MS spectra | 9 [show] |
| Best localized sequence | R.LLFNDVQTLK#DGR.H |
| Matching Proteins |
|
| Site Position | 471 |
|---|---|
| MS/MS spectra | 22 [show] |
| Best localized sequence | R.LK#AGVAAPATQVAQVTLQSVQR.R |
| Matching Proteins |
|
| Site Position | 581 |
|---|---|
| MS/MS spectra | 13 [show] |
| Best localized sequence | R.LDLQYAK#LLNSSK.A |
| Matching Proteins |
|
| Site Position | 749 |
|---|---|
| MS/MS spectra | 53 [show] |
| Best localized sequence | R.LEDLLQDAQDEK#EQLNEYK.G |
| Matching Proteins |
|
| Site Position | 1006 |
|---|---|
| MS/MS spectra | 24 [show] |
| Best localized sequence | R.IAEQQK#AQAEVEGLGK.G |
| Matching Proteins |
|
| Site Position | 1027 |
|---|---|
| MS/MS spectra | 13 [show] |
| Best localized sequence | R.LSAEAEK#VLALPEPSPAAPTLR.S |
| Matching Proteins |
|
| Site Position | 1051 |
|---|---|
| MS/MS spectra | 431 [show] |
| Best localized sequence | R.SELELTLGK#LEQVR@.S |
| Matching Proteins |
|
| Site Position | 1091 |
|---|---|
| MS/MS spectra | 137 [show] |
| Best localized sequence | R.AHEEQLK#EAQAVPATLPELEATK.A |
| Matching Proteins |
|
| Site Position | 1251 |
|---|---|
| MS/MS spectra | 29 [show] |
| Best localized sequence | R.FAK#QYINAIK.D |
| Matching Proteins |
|
| Site Position | 1258 |
|---|---|
| MS/MS spectra | 3 [show] |
| Best localized sequence | K.QYINAIK#DYELQLVTYK.A |
| Matching Proteins |
|
| Site Position | 1268 |
|---|---|
| MS/MS spectra | 45 [show] |
| Best localized sequence | K.DYELQLVTYK#AQLEPVASPAK.K |
| Matching Proteins |
|
| Site Position | 1349 |
|---|---|
| MS/MS spectra | 2 [show] |
| Best localized sequence | R.LAEVEAALEK#QR.Q |
| Matching Proteins |
|
| Site Position | 1559 |
|---|---|
| MS/MS spectra | 17 [show] |
| Best localized sequence | R.SAEAELQSK#R.A |
| Matching Proteins |
|
| Site Position | 2491 |
|---|---|
| MS/MS spectra | 1 [show] |
| Best localized sequence | R.FIEQEK#AK.L |
| Matching Proteins |
|
| Site Position | 2504 |
|---|---|
| MS/MS spectra | 1 [show] |
| Best localized sequence | K.LEQLFQDEVAK#AQQLR.E |
| Matching Proteins |
|
| Site Position | 2772 |
|---|---|
| MS/MS spectra | 8 [show] |
| Best localized sequence | K.DPYTGQQISLFQAMQK#GLIVR.E |
| Matching Proteins |
|
| Site Position | 2829 |
|---|---|
| MS/MS spectra | 13 [show] |
| Best localized sequence | R.VLADPSDDTK#GFFDPNTHENLTYLQLLER.C |
| Matching Proteins |
|
| Site Position | 2868 |
|---|---|
| MS/MS spectra | 3 [show] |
| Best localized sequence | K.AAK#GGELVYTDSEAR.D |
| Matching Proteins |
|
| Site Position | 3157 |
|---|---|
| MS/MS spectra | 52 [show] |
| Best localized sequence | R.ADAK#AYSDPSTGEPATYGELQQR.C |
| Matching Proteins |
|
| Site Position | 3225 |
|---|---|
| MS/MS spectra | 19 [show] |
| Best localized sequence | K.TPVEVPVGGFK#GR.T |
| Matching Proteins |
|
| Site Position | 3431 |
|---|---|
| MS/MS spectra | 3 [show] |
| Best localized sequence | R.DPYSGSTISLFQAMQK#GLVLR.Q |
| Matching Proteins |
|
| Site Position | 3488 |
|---|---|
| MS/MS spectra | 12 [show] |
| Best localized sequence | R.VLADPSDDTK#GFFDPNTHENLTYR@.Q |
| Matching Proteins |
|
| Site Position | 3809 |
|---|---|
| MS/MS spectra | 17 [show] |
| Best localized sequence | R.GYLNK#DTHDQLSEPSEVR.S |
| Matching Proteins |
|
| Site Position | 3868 |
|---|---|
| MS/MS spectra | 1 [show] |
| Best localized sequence | R.K#QITMEELVR.S |
| Matching Proteins |
|
| Site Position | 3901 |
|---|---|
| MS/MS spectra | 2 [show] |
| Best localized sequence | R.EGLTSIEEVTK#NLQK.F |
| Matching Proteins |
|
| Site Position | 3979 |
|---|---|
| MS/MS spectra | 1 [show] |
| Best localized sequence | R.MGIVGPEFK#DK.L |
| Matching Proteins |
|
| Site Position | 3993 |
|---|---|
| MS/MS spectra | 1 [show] |
| Best localized sequence | R.AVTGYK#DPYSGK.L |
| Matching Proteins |
|
| Site Position | 3999 |
|---|---|
| MS/MS spectra | 1 [show] |
| Best localized sequence | K.DPYSGK#LISLFQAMK.K |
| Matching Proteins |
|
| Site Position | 4046 |
|---|---|
| MS/MS spectra | 4 [show] |
| Best localized sequence | R.LPVEVAYK#R.G |
| Matching Proteins |
|
| Site Position | 4128 |
|---|---|
| MS/MS spectra | 24 [show] |
| Best localized sequence | R.VVIVDPETGK#EMSVYEAYR.K |
| Matching Proteins |
|
| Site Position | 4189 |
|---|---|
| MS/MS spectra | 20 [show] |
| Best localized sequence | R.QYDIDDAIAK#NLIDR.S |
| Matching Proteins |
|
| Site Position | 4354 |
|---|---|
| MS/MS spectra | 1 [show] |
| Best localized sequence | K.K#GWLYYEAGQR.F |
| Matching Proteins |
|
| Site Position | 4450 |
|---|---|
| MS/MS spectra | 140 [show] |
| Best localized sequence | R.LLEAAAQSTK#GYYSPYSVSGSGSTAGSR@.T |
| Matching Proteins |
|